A comparison of hair and serum trace elements in patients with Alzheimer disease and healthy participants

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dc.authoridKOC, EMINE RABIA/0000-0002-0264-7284|Karapirli, Mustafa/0000-0001-5735-9960
dc.contributor.authorKoc, Emine Rabia
dc.contributor.authorIlhan, Atilla
dc.contributor.authorAyturk, Zubeyde
dc.contributor.authorAcar, Burcu
dc.contributor.authorGurler, Mukaddes
dc.contributor.authorAltuntas, Aynur
dc.contributor.authorKarapirli, Mustafa
dc.date.accessioned2025-10-24T18:09:56Z
dc.date.available2025-10-24T18:09:56Z
dc.date.issued2015
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractBackground/aim: To determine whether there was a difference between serum and hair trace elements' concentrations in patients with Alzheimer disease (AD) and healthy participants. Materials and methods: Hair and serum copper, selenium, zinc, magnesium, manganese, and iron levels were measured by inductively coupled plasma-mass spectrometry in patients with AD and healthy participants, and the obtained results were statistically compared. Results: The mean hair selenium and zinc levels of patients with AD were significantly lower than the levels found for control participants (P < 0.05). Patients with AD had significantly higher mean hair copper and manganese levels than the controls. There were no significant differences between AD patients and controls with respect to the hair iron and magnesium levels (P > 0.05). Hair and serum trace element (copper, selenium, zinc, magnesium, manganese, and iron) levels in patients with AD showed no significant difference according to mini mental test scores or sex (P > 0.05). Conclusion: Some trace element levels may change in patients with AD. Due to the more permanent status, the analysis of these element levels in hair might be superior to blood analysis.
dc.description.sponsorshipScientific Research Fund of Turgut Ozal University [10494]
dc.description.sponsorshipThis work was supported by the Scientific Research Fund of Turgut Ozal University under project number 10494.
dc.identifier.doi10.3906/sag-1407-67
dc.identifier.endpage1039
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue5
dc.identifier.pmid26738344
dc.identifier.scopus2-s2.0-84943257635
dc.identifier.scopusqualityQ1
dc.identifier.startpage1034
dc.identifier.trdizinid180076
dc.identifier.urihttps://doi.org/10.3906/sag-1407-67
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/180076
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3880
dc.identifier.volume45
dc.identifier.wosWOS:000362526300009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherTubitak Scientific & Technological Research Council Turkey
dc.relation.ispartofTurkish Journal Of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectAlzheimer disease; trace element; hair; serum
dc.titleA comparison of hair and serum trace elements in patients with Alzheimer disease and healthy participants
dc.typeArticle

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