A Case of Neuroleptic Malignant Syndrome After COVID-19 Vaccination and Possible Mechanisms of Vaccines in the Formation of This Syndrome

Basit Öğe Kaydı
dc.authorid0000-0001-7069-769Xen_US
dc.authorid0000-0002-3131-6564en_US
dc.contributor.authorTaşcı, İrem
dc.contributor.authorUğur, Kerim
dc.date.accessioned2022-07-01T11:35:12Z
dc.date.available2022-07-01T11:35:12Z
dc.date.issued2022en_US
dc.departmentMTÖ Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionİrem Taşcı, Department of Neurology, Malatya Turgut Özal University Medical School, Malatya, Turkey. Kerim Uğur, Department of Psychiatry, Malatya Turgut Özal University Medical School, Malatya, Turkey.en_US
dc.descriptionFormerly known as:Klinik Psikofarmakoloji Bultenien_US
dc.descriptionReceived: November 8, 2021 Accepted: February 28, 2022en_US
dc.description.abstractNeuroleptic malignant syndrome COVID-19 Vaccine Fatal Complicationen_US
dc.description.abstractNeuroleptic malignant syndrome is characterized by muscle stiffness, hyperthermia, autonomic dysfunction, elevation in serum creatine phosphokinase, and changes in consciousness, which usually occur due to the side effects of life-threatening neuroleptic and antipsychotic drugs, and it can cause high mortality. A few cases of neuroleptic malignant syndrome associated with coronavirus disease 2019 infection and vaccination have been reported in the literature. Our case presented with epileptic seizure and neuroleptic malignant syndrome signs 10 days after receiving a single dose of the BNT162b2 vaccine when under low-dose olanzapine treatment with a diagnosis of autism and epilepsy. According to the laboratory test, the creatine kinase value was very high, there was hyponatremia, and the iron value was low. The patient died. Our aim in reporting this case is to draw attention to the possibility that coronavirus disease 2019 vaccines may trigger neuroleptic malignant syndrome, which can be a fatal complication in patients taking antipsychotics, albeit very rare among the large vaccinated population.en_US
dc.identifier.citationTaşcı, İ., & Uğur, K. (2022). A Case of Neuroleptic Malignant Syndrome After COVID-19 Vaccination and Possible Mechanisms of Vaccines in the Formation of This Syndrome. Psychiatry and Clinical Psychopharmacology. 32(1) 89-92.en_US
dc.identifier.doi10.5152/pcp.2022.21288
dc.identifier.endpage92en_US
dc.identifier.issn2475-0573en_US
dc.identifier.issn2475-0581en_US
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85129976533en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage89en_US
dc.identifier.urihttps://doi.org/10.5152/pcp.2022.21288
dc.identifier.urihttps://hdl.handle.net/20.500.12899/1149
dc.identifier.volume32en_US
dc.identifier.wosWOS:000788265100012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorTaşcı, İrem
dc.institutionauthorUğur, Kerim
dc.language.isoenen_US
dc.publisherTaylor & Francisen_US
dc.relation.ispartofPsychiatry and Clinical Psychopharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNeuroleptic malignant syndromeen_US
dc.subjectCOVID-19en_US
dc.subjectVaccineen_US
dc.subjectFatalen_US
dc.subjectComplicationen_US
dc.titleA Case of Neuroleptic Malignant Syndrome After COVID-19 Vaccination and Possible Mechanisms of Vaccines in the Formation of This Syndromeen_US
dc.typeArticleen_US

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