A new biological marker candidate in female reproductive system diseases: Matrix metalloproteinase with thrombospondin motifs (ADAMTS)

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dc.authoridSARIKAYA, ESMA/0000-0002-8522-7364;
dc.contributor.authorDemircan, Kadir
dc.contributor.authorComertoglu, Ismail
dc.contributor.authorAkyol, Sumeyya
dc.contributor.authorYigitoglu, Beyza Nur
dc.contributor.authorSarikaya, Esma
dc.date.accessioned2025-10-24T18:10:08Z
dc.date.available2025-10-24T18:10:08Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractPlaying a key role in the pathophysiology of many diseases, A Disintegrin-like and Metalloproteinase with Thrombospondin type-1 motif (ADAMTS) proteinases have been attracted more attention in obstetrics and gynecology. First discovered in 1997, this zinc-dependent proteinase family has 19 members today. These enzymes, which are located in the extracellular matrix (ECM), have a lot of very important functions, like matrix formation and resorption, angiogenesis, ovulation, and coagulation. In addition, in the pathogenesis of cancer, inflammation, arthritis, and connective tissue diseases, ADAMTS proteinases have crucial roles. The purpose of this review is to collect previous studies about obstetrics and gynecology that are related to ADAMTS enzymes and discuss the subject in many aspects to give an idea to the investigators who are interested in the subject.
dc.description.sponsorshipTUBITAK
dc.description.sponsorshipThis study has recevied financial support from TUBITAK.
dc.identifier.doi10.5152/jtgga.2014.14206
dc.identifier.endpage255
dc.identifier.issn1309-0399
dc.identifier.issn1309-0380
dc.identifier.issue4
dc.identifier.pmid25584036
dc.identifier.scopus2-s2.0-84919707923
dc.identifier.scopusqualityQ3
dc.identifier.startpage250
dc.identifier.trdizinid163933
dc.identifier.urihttps://doi.org/10.5152/jtgga.2014.14206
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/163933
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3980
dc.identifier.volume15
dc.identifier.wosWOS:000420676800011
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofJournal Of The Turkish-German Gynecological Association
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectADAMTS; reproductive diseases; biological marker
dc.titleA new biological marker candidate in female reproductive system diseases: Matrix metalloproteinase with thrombospondin motifs (ADAMTS)
dc.typeReview Article

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