In Vivo and In Vitro Antneoplastic Actions of Caffeic Acid Phenethyl Ester (CAPE): Therapeutic Perspectives
Küçük Resim Yok
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Routledge Journals, Taylor & Francis Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Cancer prevention and treatment strategies have attracted increasing interest. Caffeic acid phenethyl ester (CAPE), an active component of propolis extract, specifically inhibits NF-B at M concentrations and shows ability to stop 5-lipoxygenase-catalyzed oxygenation of linoleic acid and arachidonic acid. Previous studies have demonstrated that CAPE exhibits antioxidant, antiinflammatory, antiproliferative, cytostatic, antiviral, antibacterial, antifungal, and, most improtantly, antineoplastic properties. The primary goal of the present review is to summarize and critically evaluate the current knowledge regarding the anticancer effect of CAPE in different cancer types.
Açıklama
Anahtar Kelimeler
Factor-Kappa-B; Human Breast-Cancer; C6 Glioma-Cells; Leukemia Hl-60 Cells; Aberrant Crypt Foci; Intercellular Communication; Polyphenolic Compounds; Oxidative Stress; Epithelial-Cells; Rat Colon
Kaynak
Nutrition And Cancer-An International Journal
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
65
Sayı
4
