Determination of characterization, antibacterial and drug release properties of POSSbased film synthesized with sol-gel technique

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Küçük Resim

Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

TÜBİTAK

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

In the study, antibacterial film synthesis was aimed using sol-gel technique from POSS structure with various functional groups. For this purpose, antibacterial properties have been acquired by metronidazole to the films to be synthesized. The films obtained were coated on glass surface samples by dip coating method. Antibacterial activities of surface coated glass samples were observed in E.coli and S. aureus bacteria. Metronidazole release studies in the film samples were followed by UV spectrophotometer. It was observed that drug release reached 68.90% at the end of the 24th h. As a result, it is thought that the synthesized film will be a good candidate especially for biomedical surface coating areas.

Açıklama

Anahtar Kelimeler

antibacterial activity, dip coating, drug delivery, Polyhedral oligomeric silsesquioxane

Kaynak

Turkish Journal of Chemistry

WoS Q Değeri

Q4

Scopus Q Değeri

Q3

Cilt

45

Sayı

6

Künye

KARACA AÇARI, İ., KÖYTEPE, S., ATEŞ, B., Yilmaz, I., & Seckin, T. (2021). Determination of characterization, antibacterial and drug release properties of POSS-based film synthesized with sol-gel technique. Turkish Journal of Chemistry, 45(6).