Use of aromatase inhibitors in practice of gynecology

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dc.contributor.authorUsluogullari, Betul
dc.contributor.authorDuvan, Candan Zehra
dc.contributor.authorUsluogullari, Celil Alper
dc.date.accessioned2025-10-24T18:09:34Z
dc.date.available2025-10-24T18:09:34Z
dc.date.issued2015
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractPurpose: The conversion of androgens into estrogens by aromatase is called aromatization and is inhibited by aromatase inhibitors (AIs). The aim of this article is to evaluate the use of aromatase inhibitors in gynecological diseases such as endometriosis, leiomyoma, estrogen-dependent gynecologic neoplasia and infertility. Methods: This is a review of literature combined with experience and use of aromatase inhibitors in practice of gynecology. Conclusion: AIs are promising agents in treatment of estrogen dependent disease. However lack of experience, side effects and cost are limiting factors for using these agents in infertility treatment. However there is need for larger, well designed randomized trials to generate robust data in order to establish the true potential of aromatase inhibitors.
dc.identifier.doi10.1186/s13048-015-0131-9
dc.identifier.issn1757-2215
dc.identifier.pmid25824050
dc.identifier.scopus2-s2.0-84928744831
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1186/s13048-015-0131-9
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3703
dc.identifier.volume8
dc.identifier.wosWOS:000350847300001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBmc
dc.relation.ispartofJournal Of Ovarian Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectBreast-Cancer; Ovarian Stimulation; Uterine Leiomyoma; Controlled-Trial; Letrozole; Ovulation; Women; Endometriosis; Therapy; Gene
dc.titleUse of aromatase inhibitors in practice of gynecology
dc.typeReview Article

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