Use of aromatase inhibitors in practice of gynecology
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Bmc
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Purpose: The conversion of androgens into estrogens by aromatase is called aromatization and is inhibited by aromatase inhibitors (AIs). The aim of this article is to evaluate the use of aromatase inhibitors in gynecological diseases such as endometriosis, leiomyoma, estrogen-dependent gynecologic neoplasia and infertility. Methods: This is a review of literature combined with experience and use of aromatase inhibitors in practice of gynecology. Conclusion: AIs are promising agents in treatment of estrogen dependent disease. However lack of experience, side effects and cost are limiting factors for using these agents in infertility treatment. However there is need for larger, well designed randomized trials to generate robust data in order to establish the true potential of aromatase inhibitors.
Açıklama
Anahtar Kelimeler
Breast-Cancer; Ovarian Stimulation; Uterine Leiomyoma; Controlled-Trial; Letrozole; Ovulation; Women; Endometriosis; Therapy; Gene
Kaynak
Journal Of Ovarian Research
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
8
