Lung cancer and epigenetic modifications

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dc.authoridDarilmaz, Gulbahar/0000-0002-1134-404X
dc.contributor.authorYuce, Gulbahar Darilmaz
dc.contributor.authorErsoy, Ebru Ortac
dc.date.accessioned2025-10-24T18:10:11Z
dc.date.available2025-10-24T18:10:11Z
dc.date.issued2016
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractEpigenetic alterations, including DNA methylation, histone modifications, and noncoding RNA expression, have been reported to play a major role in the genesis of lung cancer. DNA methylation, histone modifications, and RNA expression are epigenetic markers in assesment of early detection, prognosis and evaluation of treatment of lung cancer. In this rewiev we summarize the common epigenetic changes associated with lung cancer to give some clarity to its etiology, and to provide an overview of the potential translational applications of these changes, including applications for early detection, diagnosis, prognostication, and therapeutics.
dc.identifier.doi10.5578/tt.10231
dc.identifier.endpage170
dc.identifier.issn0494-1373
dc.identifier.issue2
dc.identifier.pmid27481083
dc.identifier.scopus2-s2.0-84977487665
dc.identifier.scopusqualityQ3
dc.identifier.startpage163
dc.identifier.urihttps://doi.org/10.5578/tt.10231
dc.identifier.urihttps://hdl.handle.net/20.500.12899/4032
dc.identifier.volume64
dc.identifier.wosWOS:000386264100009
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isotr
dc.publisherTurkish Assoc Tuberculosis & Thorax
dc.relation.ispartofTuberkuloz Ve Torak-Tuberculosis And Thorax
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectLung cancer; epigenetics; chromatin; histone modifications; DNA methylation
dc.titleLung cancer and epigenetic modifications
dc.title.alternativeAkciğer kanseri ve epigenetik değişiklikler
dc.typeReview Article

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