Lung cancer and epigenetic modifications
Küçük Resim Yok
Tarih
2016
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turkish Assoc Tuberculosis & Thorax
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Epigenetic alterations, including DNA methylation, histone modifications, and noncoding RNA expression, have been reported to play a major role in the genesis of lung cancer. DNA methylation, histone modifications, and RNA expression are epigenetic markers in assesment of early detection, prognosis and evaluation of treatment of lung cancer. In this rewiev we summarize the common epigenetic changes associated with lung cancer to give some clarity to its etiology, and to provide an overview of the potential translational applications of these changes, including applications for early detection, diagnosis, prognostication, and therapeutics.
Açıklama
Anahtar Kelimeler
Lung cancer; epigenetics; chromatin; histone modifications; DNA methylation
Kaynak
Tuberkuloz Ve Torak-Tuberculosis And Thorax
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
64
Sayı
2
