Caffeic Acid Phenethyl Ester: Its Protective Role Against Certain Major Eye Diseases
Küçük Resim Yok
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Mary Ann Liebert, Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
As an effective compound found mainly in the honeybee product propolis, caffeic acid phenethyl ester (CAPE) has been commonly utilized as a medicine and remedial agent, in a number of countries. Specifically, it might inhibit nuclear factor kappa B at micromolar concentrations and demonstrate antioxidant, antineoplastic, antiproliferative, cytostatic, antiviral, antibacterial, antifungal, and anti-inflammatory features. This review article summarizes the recent progress regarding the favorable effects of CAPE on a number of eye disease models, including cataract and posterior capsule opacification, corneal diseases, retina and optic nerve-related diseases, ischemia/reperfusion injury of retina, inflammation and infection-related diseases. CAPE has been found to exhibit promising efficacy, with minimal adverse effects, in animal and cell culture studies of several eye diseases.
Açıklama
Anahtar Kelimeler
Staphylococcus-Epidermidis Endophthalmitis; Endotoxin-Induced Uveitis; Endothelial Growth-Factor; Pigment Epithelial-Cells; Induced Diabetic-Rats; Ischemia-Reperfusion; Oxidative Stress; Mouse Skin; Proliferative Vitreoretinopathy; Ischemia/Reperfusion Injury
Kaynak
Journal Of Ocular Pharmacology And Therapeutics
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
30
Sayı
9
