Does vitamin E prevent tubal damage caused by smoking? A light microscopy and animal study

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dc.authoridKosus, Nermin/0000-0003-2390-9498
dc.contributor.authorDuran, Muzeyyen
dc.contributor.authorUstunyurt, Emin
dc.contributor.authorKosus, Aydin
dc.contributor.authorKosus, Nermin
dc.contributor.authorTurhan, Nilgun
dc.contributor.authorHizli, Deniz
dc.contributor.authorSarac, Gulce Naz
dc.date.accessioned2025-10-24T18:09:00Z
dc.date.available2025-10-24T18:09:00Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractObjective: To assess the histomorphological effects of smoking on the cilia of fallopian tubes in mice and the effect of vitamin E on the negative effects of smoke. Study design: Eighteen 12-14 week-old Swiss albino type female mice were randomly divided into three groups, each consisting of six mice: Group A: control group; Group B: mice exposed to cigarette smoke; Group C: mice exposed to cigarette smoke together with vitamin E. Groups B and C were exposed to cigarette smoke for 10 weeks. After 10 weeks, tubal excision was performed in all animals. Histopathologic examination of excised tubal tissue was conducted under light microscopy. Results: The number of cilia was significantly lower in Group B. Although not statistically significant, the median number of cilia in Group C was measured to be higher than in Group B but lower than in Group A. Conclusion: Based on the results, it can be concluded that smoking decreases tubal cilia numbers. Supplementation by vitamin E may treat or at least help to slow down the decrease in number of cilia caused by smoking; therefore it could be used therapeutically in the treatment of smoking-related tubal damage. Crown Copyright (C) 2014 Published by Elsevier Ireland Ltd. All rights reserved.
dc.identifier.doi10.1016/j.ejogrb.2014.01.020
dc.identifier.endpage151
dc.identifier.issn0301-2115
dc.identifier.issn1872-7654
dc.identifier.pmid24530190
dc.identifier.scopus2-s2.0-84898058077
dc.identifier.scopusqualityQ2
dc.identifier.startpage149
dc.identifier.urihttps://doi.org/10.1016/j.ejogrb.2014.01.020
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3416
dc.identifier.volume175
dc.identifier.wosWOS:000335432000027
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Science Bv
dc.relation.ispartofEuropean Journal Of Obstetrics & Gynecology And Reproductive Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectSmoking; Fallopian tubes; Infertility; Cilia number; Vitamin E
dc.titleDoes vitamin E prevent tubal damage caused by smoking? A light microscopy and animal study
dc.typeArticle

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