The association between plasma visfatin levels and ED

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dc.authoridYILDIRIM, MEHMET/0000-0003-4768-4537
dc.contributor.authorKaratas, O. F.
dc.contributor.authorYildirim, M. E.
dc.contributor.authorCelik, H. T.
dc.contributor.authorBadem, H.
dc.contributor.authorCavis, M.
dc.contributor.authorCimentepe, E.
dc.date.accessioned2025-10-24T18:09:12Z
dc.date.available2025-10-24T18:09:12Z
dc.date.issued2015
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractVisfatin was initially proposed as a clinical marker of atherosclerosis, endothelial dysfunction and vascular damage, with a potential prognostic value. It has been shown that endothelial dysfunction has an important role in ED. We aimed to determine the levels of visfatin in ED patients and characterize the relationship between visfatin levels and ED. This case-control study was conducted between October 2010 and August 2012, and 41 severe ED patients (group 1) and 36 healthy controls (group 2) were involved. Fasting visfatin level was measured with enzyme-linked immunosorbent assay method. The groups were compared in terms of some clinical (height, weight and body mass index) and biochemical parameters (glucose, triglycerides, cholesterol, low-density lipoprotein and high-density lipoprotein). No statistically significant difference in the visfatin levels was found between the patients and the controls (17, 5 +/- 14.4, 14, 9 +/- 7 and 9, respectively, P=0.399). No difference in the other clinical and biochemical parameters was observed between the two groups. No significant difference in the serum visfatin levels of ED patients compared with healthy patients was noticed. Further studies are needed to confirm the effect of visfatin on cardiometabolic diseases and ED, indeed.
dc.identifier.doi10.1038/ijir.2015.1
dc.identifier.endpage160
dc.identifier.issn0955-9930
dc.identifier.issn1476-5489
dc.identifier.issue4
dc.identifier.pmid25693971
dc.identifier.scopus2-s2.0-84937164344
dc.identifier.scopusqualityQ1
dc.identifier.startpage157
dc.identifier.urihttps://doi.org/10.1038/ijir.2015.1
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3515
dc.identifier.volume27
dc.identifier.wosWOS:000358111400007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherNature Publishing Group
dc.relation.ispartofInternational Journal Of Impotence Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectErectile Dysfunction; Endothelial Dysfunction; Metabolic Syndrome; International Index; Testosterone; Obesity; Fat
dc.titleThe association between plasma visfatin levels and ED
dc.typeArticle

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