Usefulness of Neutrophil/Lymphocyte Ratio as a Predictor of Amputation after Embolectomy for Acute Limb Ischemia

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dc.authoridTasoglu, Irfan/0000-0001-7714-0296|DILLI, DILEK/0000-0003-2634-2562|DEMIR, ZELIHA ASLI/0000-0003-3053-0443|Cicek, Omer Faruk/0000-0002-4675-3273;
dc.contributor.authorTasoglu, Irfan
dc.contributor.authorCicek, Omer Faruk
dc.contributor.authorLafci, Gokhan
dc.contributor.authorKadirogullari, Ersin
dc.contributor.authorSert, Dogan Emre
dc.contributor.authorDemir, Asli
dc.contributor.authorCavus, Umut
dc.date.accessioned2025-10-24T18:08:58Z
dc.date.available2025-10-24T18:08:58Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractBackground: The aim of this study was to examine the predictive ability of admission neutrophil/lymphocyte ratio (NLR) for predicting amputation in patients with acute limb ischemia who underwent embolectomy. Methods: We retrospectively analyzed the clinical, hematologic, and amputation data of 254 patients who had undergone embolectomy for acute limb ischemia. There were 152 (52%) men and 93 (48%) women, with a mean age of 66.04 +/- 13.30 years. The admission NLR was determined by dividing the absolute neutrophil count by the absolute lymphocyte count. The primary end point was determined as amputation and death. Results: The mean duration of follow-up was 26 months. During the follow-up period, there were 18 (7%) amputations within 30 days of surgery and 36 (15%) amputations over a mean follow-up of 26 months. Based on multivariate logistic regression modeling, no arterial back bleeding and preoperative NLR were observed to be independent risk factors for amputation within 30 days of surgery, and no arterial back bleeding and preoperative NLR were observed to be independent risk factors for midterm amputation for the same time period. A NLR of >= 5.2 was taken as the cutoff based upon the receiver operating characteristic. In receiver operating characteristic curve analysis, a NLR >= 5.2 had 83% sensitivity and 63% specificity in predicting amputation within 30 days of surgery and 63% sensitivity and 63% specificity in predicting midterm amputation. Conclusions: An elevated NLR is associated with a poorer limb survival after embolectomy. This simple, inexpensive test may therefore be added to risk stratification of these high-risk patients.
dc.identifier.doi10.1016/j.avsg.2012.12.009
dc.identifier.endpage613
dc.identifier.issn0890-5096
dc.identifier.issn1615-5947
dc.identifier.issue3
dc.identifier.pmid24084272
dc.identifier.scopus2-s2.0-84897081782
dc.identifier.scopusqualityQ2
dc.identifier.startpage606
dc.identifier.urihttps://doi.org/10.1016/j.avsg.2012.12.009
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3385
dc.identifier.volume28
dc.identifier.wosWOS:000333252600014
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Science Inc
dc.relation.ispartofAnnals Of Vascular Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectNeutrophil-Lymphocyte Ratio; Long-Term Mortality; Acute Leg Ischemia; Preoperative Neutrophil; Elevated Neutrophil; Survival; Thrombolysis; Inflammation; Management; Resection
dc.titleUsefulness of Neutrophil/Lymphocyte Ratio as a Predictor of Amputation after Embolectomy for Acute Limb Ischemia
dc.title.alternativeUsefulness of neutrophil/lymphocyte ratio as a predictor of amputation after embolectomy for acute limb ischemia
dc.typeArticle

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