Usefulness of the Platelet-to-Lymphocyte Ratio in Predicting Angiographic Reflow After Primary Percutaneous Coronary Intervention in Patients With Acute ST-Segment Elevation Myocardial Infarction

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dc.authorid, Mustafa Cetin/0000-0001-7542-6602|Yarlioglues, Mikail/0000-0001-8905-9807;
dc.contributor.authorKurtul, Alparslan
dc.contributor.authorYarlioglues, Mikail
dc.contributor.authorMurat, Sani Namik
dc.contributor.authorErgun, Gokhan
dc.contributor.authorDuran, Mustafa
dc.contributor.authorKasapkara, Haci Ahmet
dc.contributor.authorDemircelik, Muhammed Bora
dc.date.accessioned2025-10-24T18:08:58Z
dc.date.available2025-10-24T18:08:58Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractImpaired coronary flow after primary percutaneous coronary intervention (PPCI) is associated with short- and long-term morbidity and mortality in patients with acute ST-segment elevation myocardial infarction (STEMI). Recent studies have demonstrated that platelet-to-lymphocyte ratio (PLR) is associated with adverse cardiovascular outcomes. The aim of this study was to assess the relation between admission PLR and angiographic reflow after PPCI. A total of 520 patients with acute STEMI (age 60 +/- 13 years; 74% men) occurring within 12 hours of the onset of symptoms who underwent PPCI were enrolled. The PLR and other laboratory parameters were measured before PPCI. The patients were divided into 2 groups based on the postintervention Thrombolysis in Myocardial Infarction (TIMI) flow grade: normal-reflow group (defined as postintervention TIMI grade 3 flow) and none-reflow group (consisted of both patients with angiographic no-reflow defined as postintervention TIMI grades 0 to 1 flow and slow flow defined as postintervention TIMI grade 2 flow). There were 117 patients (22.5%) in the none-reflow group (age 68 +/- 13 years and 77% men) and 403 patients in the normal-reflow group (age 58 +/- 12 years and 63% men). The none-reflow group had significantly higher PLR compared with the normal-reflow group (219 79 vs 115 +/- 59, p <0.001). In logistic regression analysis, PLR (odds ratio 1.818, 95% confidence interval 1.713 to 1.980, p <0.001) and total stent length (OR 1.052, confidence interval 1.019 to 1.086, p = 0.002) were independent predictors of none-reflow after PPCI. In conclusion, preintervention PLR is a strong and independent predictor of slow flow/no-reflow after PPCI in patients with acute STEMI. (C) 2014 Elsevier Inc. All rights reserved.
dc.identifier.doi10.1016/j.amjcard.2014.04.045
dc.identifier.endpage347
dc.identifier.issn0002-9149
dc.identifier.issn1879-1913
dc.identifier.issue3
dc.identifier.pmid24948493
dc.identifier.scopus2-s2.0-84904265520
dc.identifier.scopusqualityQ2
dc.identifier.startpage342
dc.identifier.urihttps://doi.org/10.1016/j.amjcard.2014.04.045
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3377
dc.identifier.volume114
dc.identifier.wosWOS:000339641700003
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherExcerpta Medica Inc-Elsevier Science Inc
dc.relation.ispartofAmerican Journal Of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectNo-Reflow; Prognostic Value; Neutrophil/Lymphocyte Ratio; Activation; Impact; Flow; Angioplasty
dc.titleUsefulness of the Platelet-to-Lymphocyte Ratio in Predicting Angiographic Reflow After Primary Percutaneous Coronary Intervention in Patients With Acute ST-Segment Elevation Myocardial Infarction
dc.title.alternativeUsefulness of the platelet-to-lymphocyte ratio in predicting angiographic reflow after primary percutaneous coronary intervention in patients with acute st-segment elevation myocardial infarction
dc.typeArticle

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