Evaluation of Choroidal Thickness in Amblyopia Using Enhanced Depth Imaging Optical Coherence Tomography

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dc.authoriddervisogullari, mehmet serdar/0000-0003-2006-2906
dc.contributor.authorTenlik, Aylin
dc.contributor.authorGuler, Emre
dc.contributor.authorKulak, Ali Ender
dc.contributor.authorTotan, Yuksel
dc.contributor.authorDervisogullari, Mehmet Serdar
dc.contributor.authorGuragac, Fatma Betul
dc.date.accessioned2025-10-24T18:09:44Z
dc.date.available2025-10-24T18:09:44Z
dc.date.issued2015
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractPurpose: To evaluate the choroidal thickness (CT) in hyperopic anisometropic amblyopic eyes, fellow non-amblyopic eyes, and age-matched normal eyes, using spectral-domain optical coherence tomography (SD-OCT). Materials and methods: In total 53 subjects (17.8 +/- 11.0 years, mean +/- SD) with hyperopic anisometropic amblyopia (AE) and 53 age-matched controls (17.7 +/- 11.0 years) were included in this prospective study. Each subject underwent a dilated eye examination, cycloplegic refraction and axial length (AL) measurement using Nidek AL-Scan optical biometer (Nidek CO, Aichi, Japan). The CT of subfoveal area and at a radius of 1 and 3mm around the fovea was determined using the enhanced depth imaging program of a SD-OCT (Cirrus HD OCT, Carl-Zeiss Meditec, Dublin, CA). CT, AL and spherical equivalent refraction (SER) of the amblyopic eyes were compared to that of the fellow and control eyes. Results: The mean subfoveal CTwas 305.6 +/- 26.0 mm in the amblyopic eyes, 282.6 +/- 30.7 mm in the fellow eyes and 280.1 +/- 8.8 in the control eyes. The subfoveal choroid in amblyopic eyes was significantly thicker than that of the fellow eyes and control eyes (p<0.001). There was a significant negative correlation between the subfoveal CT and the AL in amblyopic (r=-0.298, p=0.03) eyes but not in the control and fellow eyes. Conclusions: The subfoveal choroid of eyes with hyperopic AE is significantly thicker than that of the fellow eye and the age-matched controls. Hence, CT seems to be effected in AE.
dc.identifier.doi10.3109/02713683.2014.971933
dc.identifier.endpage1067
dc.identifier.issn0271-3683
dc.identifier.issn1460-2202
dc.identifier.issue10
dc.identifier.pmid25379803
dc.identifier.scopus2-s2.0-84941415670
dc.identifier.scopusqualityQ1
dc.identifier.startpage1063
dc.identifier.urihttps://doi.org/10.3109/02713683.2014.971933
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3781
dc.identifier.volume40
dc.identifier.wosWOS:000361327500012
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofCurrent Eye Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectAmblyopia; choroidal thickness; enhanced depth imaging; hyperopic anisometropia; optical coherence tomography
dc.titleEvaluation of Choroidal Thickness in Amblyopia Using Enhanced Depth Imaging Optical Coherence Tomography
dc.typeArticle

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