Effect of body mass index and age on in vitro fertilization in polycystic ovary syndrome

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dc.authoridates, can/0000-0003-2286-4398|Kalem, Ziya/0000-0002-5435-2074|NAMLI KALEM, MUBERRA/0000-0002-2316-5495;
dc.contributor.authorKalem, Muberra Namli
dc.contributor.authorKalem, Ziya
dc.contributor.authorSari, Tamer
dc.contributor.authorAtes, Can
dc.contributor.authorGurgan, Timur
dc.date.accessioned2025-10-24T18:10:08Z
dc.date.available2025-10-24T18:10:08Z
dc.date.issued2016
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractObjective: The aim of this study was to investigate age-related variations in the effect of body mass index (BMI) on in vitro fertilization (IVF) outcomes. Material and Methods: This was a cohort study conducted by retrospectively investigating the IVF cycles of 653 polycystic ovary syndrome (PCOS) patients under the age of 40 years who were diagnosed based on the Rotterdam criteria in a private IVF clinic between 2005 and 2015. The study included data from 653 IVF cycles of PCOS patients. The patients were classified into three groups based on their BMI, i.e., normal weight (n=299), overweight (n=208), and obese (n=146). The patients were also grouped by age: 562 patients were under the age of 35 years and 91 patients were above the age of 35 years. Then, BMI- and age-related variations in the IVF cycle parameters and clinical pregnancy rates of patients with PCOS were investigated. The Mantel-Haenszel Chi-square statistical assessment method was used to determine whether the effect of BMI on IVF outcomes varies with age. Results: Variations in cycle variables with BMI and age showed that IVF cycles were negatively affected by increases in obesity and age. Clinical pregnancy rates were found to be lower in the obese group than in the other groups, particularly in the age group above 35 years; however, this difference could not be proven statistically. Conclusion: The present study evaluated obesity and clinical pregnancy rates in IVF cycles in PCOS patients according to age groups, and particularly in the obese group, the clinical pregnancy rates were observed to be lower in the age group >= 35 years than in the other BMI groups; however, this difference was found to be statistically insignificant.
dc.identifier.doi10.5152/jtgga.2016.15235
dc.identifier.endpage90
dc.identifier.issn1309-0399
dc.identifier.issn1309-0380
dc.identifier.issue2
dc.identifier.pmid27403074
dc.identifier.scopus2-s2.0-84973521590
dc.identifier.scopusqualityQ3
dc.identifier.startpage83
dc.identifier.urihttps://doi.org/10.5152/jtgga.2016.15235
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3982
dc.identifier.volume17
dc.identifier.wosWOS:000383256500006
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofJournal Of The Turkish-German Gynecological Association
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectPCOS; body mass index; age; IVF outcome
dc.titleEffect of body mass index and age on in vitro fertilization in polycystic ovary syndrome
dc.typeArticle

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