Evaluation of the Retinal Ganglion Cell Layer Thickness in Healthy Turkish Children

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dc.contributor.authorTotan, Yuksel
dc.contributor.authorGuragac, Fatma B.
dc.contributor.authorGuler, Emre
dc.date.accessioned2025-10-24T18:09:17Z
dc.date.available2025-10-24T18:09:17Z
dc.date.issued2015
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractPurpose:To identify the distribution, variation, and determinants of ganglion cell-inner plexiform layer (GC-IPL) thickness in healthy Turkish children measured by high-definition optical coherence tomography (HD-OCT).Patients and Methods:This institutional study involved 296 eyes from 296 healthy children aged between 3 and 17 years. Each child underwent a dilated eye examination, cycloplegic refraction, and axial length measurement using Nidek AL-Scan optical biometer. Macular scan was used to measure the GC-IPL thickness, and peripapillary retinal nerve fiber layer (RNFL) thickness was measured using the HD-OCT (Cirrus HD-OCT). Right eye of each subject was selected for analysis.Results:A total of 296 children (125 boys, 171 girls) were included in this study. The mean age of the children was 9.624.10 years (range, 3 to 17 y). The mean spherical equivalent was -0.09 +/- 1.49 D. The mean AL was 23.03 +/- 1.03 mm. The mean overall GC-IPL thickness was 83.44 +/- 5.52 m and RNFL thickness was 96.91 +/- 10.21 m. They were thicker than has been reported in adults. According to age-adjusted multiple regression analyses significant predictors of mean GC-IPL thickness were peripapillary RNFL thickness and AL (P<0.001).Conclusions:This study ensures a pediatric normative database of GC-IPL using spectral-domain OCT. This information may provide to diagnosis and monitoring of optic nerve diseases and glaucoma in children.
dc.identifier.doi10.1097/IJG.0000000000000168
dc.identifier.endpagee108
dc.identifier.issn1057-0829
dc.identifier.issn1536-481X
dc.identifier.issue5
dc.identifier.pmid25304280
dc.identifier.scopus2-s2.0-84931564824
dc.identifier.scopusqualityQ2
dc.identifier.startpagee103
dc.identifier.urihttps://doi.org/10.1097/IJG.0000000000000168
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3569
dc.identifier.volume24
dc.identifier.wosWOS:000356375700013
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofJournal Of Glaucoma
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectchildren; ganglion cell layer thickness; retinal nerve fiber layer; high-definition optical coherence tomography
dc.titleEvaluation of the Retinal Ganglion Cell Layer Thickness in Healthy Turkish Children
dc.typeArticle

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