Oxidant/antioxidant balance in the aqueous humor of patients with glaucoma

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dc.contributor.authorErgan, Esra
dc.contributor.authorOzturk, Farak
dc.contributor.authorBeyazyildiz, Emrullah
dc.contributor.authorElgin, Ufuk
dc.contributor.authorSen, Emine
dc.contributor.authorCankaya, Ali Bulent
dc.contributor.authorCelik, Tugrul
dc.date.accessioned2025-10-24T18:10:34Z
dc.date.available2025-10-24T18:10:34Z
dc.date.issued2016
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractAIM: To evaluate total antioxidant status (TAS), total oxidant status (TOS), and the oxidative stress index (OSI) of the aqueous humor (AH) in patients with glaucoma. METHODS: The prospective study was composed of a study group (n=31) and a control group (a=31). Fifteen patients in the study group were diagnosed with primary open angle glaucoma (POAG), and 16 patients were diagnosed with pseudoexfoliation glaucoma (PEG). The control group was composed of non -glaucomatous patients with cataracts. AH samples were collected and analyzed for TAS, TOS, and OSI levels. RESULTS: Mean AH TAS level was significantly higher in patients with glaucoma than that in the control group (P<0.01). Mean TOS and OSI levels tended to increase in patients with glaucoma. No significant differences in TAS, TOS, or OSI levels were observed between patients with POAG and PEG. CONCLUSION: High levels of TAS were observed in patients with glaucoma, which was likely a response to the increased oxidative stress observed in these patients.
dc.description.sponsorshipTurkish Ophthalmology Association
dc.description.sponsorshipSupported by Turkish Ophthalmology Association.
dc.identifier.endpage252
dc.identifier.issn2222-3959
dc.identifier.issn2227-4898
dc.identifier.issue2
dc.identifier.pmid26949644
dc.identifier.scopus2-s2.0-84957973968
dc.identifier.scopusqualityQ2
dc.identifier.startpage249
dc.identifier.urihttps://hdl.handle.net/20.500.12899/4263
dc.identifier.volume9
dc.identifier.wosWOS:000369551700012
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherIjo Press
dc.relation.ispartofInternational Journal Of Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectoxidative stress; primary open angle glaucoma; pseudoexfoliation glaucoma; total antioxidant status; total oxidant status
dc.titleOxidant/antioxidant balance in the aqueous humor of patients with glaucoma
dc.typeArticle

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