Drug-drug interactions in the risky population: elderly, urological patients admitted to the intensive care unit

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dc.authorid0000-0002-3745-1302en_US
dc.authorid0000-0002-8088-1009en_US
dc.contributor.authorBuğday, Muhammet Serdar
dc.contributor.authorÖksüz, Ersoy
dc.date.accessioned2021-05-18T09:17:43Z
dc.date.available2021-05-18T09:17:43Z
dc.date.issued2021en_US
dc.departmentMTÖ Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractDrug-drug interactions are a common health problem. They cause more serious side effects and are more common in patients with multiple diseases, especially in the elderly. It was aimed herein to examine the frequency of drug -drug interactions in elderly patients treated in the intensive care unit due to urological diseases. This retrospective study was performed on hospital ized patients over the age of 85 years who had urologic diseases and were treated in the intensive care unit. Drug-drug interactions were evaluated using the Rx mediapharma and Lexi interact programs. A total of 91 different medications were administered to 100 patients. Of the patients, 87 had drug-drug interactions and the total number of drug-drug interactions was 550. When all of the interactions were examined, it was observed that drug - drug interactions were most often to cause side effects on the cardiovascular system, such as arrhythmia, hypotension, or hypertension (40%). The drugs that were most involved in drug-drug interactions were furosemide (n: 87), enoxaparin sodium (n: 74), and acetyl salicylic acid (n: 45). The results of the study showed that drug-drug interactions were seen quite frequently in elderly patients hospitalized due to primary urological diseases in the intensive care unit. The most common adverse drug reactions in these patients were bleeding, changes in the therapeutic levels of drugs, and hyperkalemia.en_US
dc.identifier.citationBuğday, Muhammet Serdar & Öksüz, Ersoy. (January 01, 2021). Drug-drug interactions in the risky population: elderly, urological patients admitted to the intensive care unit. Eastern Journal of Medicine, 26, 2, 236-241.en_US
dc.identifier.doi10.5505/ejm.2021.04864
dc.identifier.endpage241en_US
dc.identifier.issn1301-0883en_US
dc.identifier.issn1339-3886en_US
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85104181025en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage236en_US
dc.identifier.urihttps://doi.org/10.5505/ejm.2021.04864
dc.identifier.urihttps://hdl.handle.net/20.500.12899/134
dc.identifier.volume26en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorBuğday, Muhammet Serdar
dc.institutionauthorÖksüz, Ersoy
dc.language.isoenen_US
dc.publisherYüzüncü Yıl Üniversitesien_US
dc.relation.ispartofEastern Journal of Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDrug-drug İnteractionsen_US
dc.subjectUrologyen_US
dc.subjectElderlyen_US
dc.subjectIntensive Care Unitsen_US
dc.titleDrug-drug interactions in the risky population: elderly, urological patients admitted to the intensive care uniten_US
dc.typeArticleen_US

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