Evaluation of Aqueous Endocan and Endostatin Levels in Patients With Pseudoexfoliation Syndrome

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dc.contributor.authorYagci, Ramazan
dc.contributor.authorDervisogullari, Serdar
dc.contributor.authorGuler, Emre
dc.contributor.authorTotan, Yueksel
dc.contributor.authorHepsen, Ibrahim F.
dc.date.accessioned2025-10-24T18:09:18Z
dc.date.available2025-10-24T18:09:18Z
dc.date.issued2019
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractPurpose: The purpose of the present study was to evaluate the aqueous humor endocan and endostatin levels in patients with pseudoexfoliation (PEX) syndrome and to compare the results with healthy individuals. Materials and Methods: Twenty nine cataract patients with PEX syndrome (PEX group) and 32 cataract patients without PEX syndrome (control group) were enrolled in the study. Endocan and endostatin were measured in the aqueous humor of the PEX and control groups by enzyme-linked immunosorbent assay. Results: There was no difference between the PEX and control groups in terms of age (P=0.721) and sex (P=0.902). The aqueous levels of endocan in patients with PEX (26.39 +/- 5.80 pg/mL) was significantly higher than in the control group (11.42 +/- 2.44 pg/mL) (P=0.039). The aqueous levels of endostatin was 12.00 +/- 1.35 ng/mL in the PEX group and 14.22 +/- 3.31 ng/mL in the control group, however, the difference was not statistically significant (P=0.41). Conclusions: The findings of the present study could suggest that the increased levels of aqueous endocan may be related to pathogenesis of PEX. However, levels of aqueous endostatin did not show any significant difference in PEX.
dc.description.sponsorshipTurgut Ozal University Research Center [2013-04-011]
dc.description.sponsorshipSupported by a grant from the Turgut Ozal University Research Center (No. 2013-04-011).
dc.identifier.doi10.1097/IJG.0000000000001115
dc.identifier.endpage41
dc.identifier.issn1057-0829
dc.identifier.issn1536-481X
dc.identifier.issue1
dc.identifier.pmid30339555
dc.identifier.scopus2-s2.0-85055321495
dc.identifier.scopusqualityQ2
dc.identifier.startpage38
dc.identifier.urihttps://doi.org/10.1097/IJG.0000000000001115
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3571
dc.identifier.volume28
dc.identifier.wosWOS:000458331300012
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofJournal Of Glaucoma
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectendocan; endostatin; aqueous; cataract; pseudoexfoliation
dc.titleEvaluation of Aqueous Endocan and Endostatin Levels in Patients With Pseudoexfoliation Syndrome
dc.typeArticle

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