Is Pentraxin 3 a New Cardiovascular Risk Marker in Polycystic Ovary Syndrome?

Basit Öğe Kaydı
dc.authoridKaygusuz, Ikbal/0000-0002-5635-505X|Sari, Umut/0000-0002-9593-9904
dc.contributor.authorSari, Umut
dc.contributor.authorKaygusuz, Ikbal
dc.contributor.authorKafali, Hasan
dc.date.accessioned2025-10-24T18:09:28Z
dc.date.available2025-10-24T18:09:28Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractBackground/Aims: Polycystic ovary syndrome (PCOS) patients have an increased rate of subclinical inflammation, which plays a role in the pathogenesis of atherosclerosis. Pentraxin 3 (PTX3) is an inflammatory mediator which belongs to the same family as the well-established cardiovascular biomarker C-reactive protein (CRP). The present study was performed to investigate plasma PTX3 levels in patients with PCOS and to determine the relationship between PTX3 and other known cardiovascular risk factors. Methods: 40 patients with PCOS and 40 age- and BMI-matched healthy controls were included in the study. The groups were divided into subgroups according to BMI. Insulin resistance indexes, lipid profile, CRP and PTX3 levels were analyzed. Results: There was no difference for insulin resistance indexes and lipid profile between the PCOS and control groups. CRP levels were significantly higher in obese PCOS and control subjects than in lean subjects, whereas no difference in PTX3 concentrations was observed between subgroups. Conclusion: PTX3 and CRP levels were similar in the PCOS group compared with the non-PCOS control group. (C) 2014 S. Karger AG, Basel
dc.identifier.doi10.1159/000363744
dc.identifier.endpage178
dc.identifier.issn0378-7346
dc.identifier.issn1423-002X
dc.identifier.issue3
dc.identifier.pmid25011417
dc.identifier.scopus2-s2.0-84908665016
dc.identifier.scopusqualityQ2
dc.identifier.startpage173
dc.identifier.urihttps://doi.org/10.1159/000363744
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3664
dc.identifier.volume78
dc.identifier.wosWOS:000342880600005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKarger
dc.relation.ispartofGynecologic And Obstetric Investigation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectPentraxin 3; Polycystic ovary syndrome; Cardiovascular disease; Body mass index; Insulin resistance
dc.titleIs Pentraxin 3 a New Cardiovascular Risk Marker in Polycystic Ovary Syndrome?
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu