Effect of Ankaferd Blood Stopper on muscle healing

Basit Öğe Kaydı
dc.authoridYAVUZ, OSMAN/0000-0003-4141-2944;
dc.contributor.authorUygun, Murat
dc.contributor.authorYavuz, Osman Y.
dc.contributor.authorUras, Ismail
dc.contributor.authorDuman, Ibrahim G.
dc.contributor.authorHaltas, Hacer
dc.contributor.authorKomurcu, Mahmut
dc.date.accessioned2025-10-24T18:10:28Z
dc.date.available2025-10-24T18:10:28Z
dc.date.issued2016
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractPurpose: Ankaferd Blood Stopper (ABS), which is a standardized mixture of herbal extracts obtained from five plants, has been proven as an efficient hemostatic agent and is still used in emergency situations. It is not known exactly if decreased bleeding has positive or negative effects on muscle healing and fibrosis, so the purpose of this study was to test the effect of ABS on muscle healing and morphology. Methods: A total of 66 outbred Wistar rats were divided into three control and three experimental subgroups. In the experimental groups, ABS was sprayed on the cut surface of the soleus. In the control groups, a saline solution was sprayed on the cut surface of the soleus. Subgroups were euthanized after 2 weeks, 3 weeks and 4 weeks, respectively. In each subgroup, eight rats were used for the biomechanical study to determine muscle healing and three rats were used for the histopathological investigation. Results: Although muscle strength in the control groups was lower than that of the experimental groups in early weeks, no differences were found between the control and the experimental groups at 4 weeks. Conclusions: ABS has no negative effect on muscle healing. We also observed that ABS accelerated muscle healing compared to the control group. ABS could be used in hemostasis of open fractures and elective orthopedic surgeries.
dc.identifier.endpageS191
dc.identifier.issn0147-958X
dc.identifier.issn1488-2353
dc.identifier.issue6
dc.identifier.pmid27917816
dc.identifier.scopus2-s2.0-85010006031
dc.identifier.scopusqualityQ2
dc.identifier.startpageS187
dc.identifier.urihttps://hdl.handle.net/20.500.12899/4180
dc.identifier.volume39
dc.identifier.wosWOS:000389725000036
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherCanadian Soc Clinical Investigation
dc.relation.ispartofClinical And Investigative Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectEfficacy
dc.titleEffect of Ankaferd Blood Stopper on muscle healing
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu