Is polycystic ovarian syndrome a risk factor for urolithiasis?

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dc.authoridKaygusuz, Ikbal/0000-0002-5635-505X;
dc.contributor.authorKaygusuz, Ikbal
dc.contributor.authorKaratas, Omer Faruk
dc.contributor.authorKafali, Hasan
dc.contributor.authorCimentepe, Ersin
dc.contributor.authorUnal, Dogan
dc.date.accessioned2025-10-24T18:08:47Z
dc.date.available2025-10-24T18:08:47Z
dc.date.issued2013
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractUrinary stone disease is a complex multifactorial disorder influenced by both intrinsic and environmental factors. It is generally known that age and sex are risk factors for urinary stone disease. Also men have higher mean urinary oxalate concentrations than women. In addition, in animal and human studies, testosterone has been shown to increase the formation of urinary stones. This suggests that sex hormones are considered to be involved in the pathogenesis of stone disease. Polycystic ovary syndrome (PCOS) is one of the most frequent endocrine disorders of women in the reproductive age, affecting 5-10 % of women in this life span. It is characterized with chronic anovulation\oligo-ovulation, clinical or biochemical evidence of hyperandrogenism and polycystic ovaries on ultrasound examination. Hyperandrogenism, the main feature of PCOS, may trigger the urinary stone formation besides hirsutism, alopecia and acne. Therefore, we hypothesize that PCOS accompanied by hyperandrogenism may be a risk factor in the formation of urinary stone disease.
dc.identifier.doi10.1007/s00240-013-0564-9
dc.identifier.endpage362
dc.identifier.issn2194-7228
dc.identifier.issue4
dc.identifier.pmid23604095
dc.identifier.scopus2-s2.0-84892366470
dc.identifier.scopusqualityQ2
dc.identifier.startpage361
dc.identifier.urihttps://doi.org/10.1007/s00240-013-0564-9
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3300
dc.identifier.volume41
dc.identifier.wosWOS:000321975800011
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofUrolithiasis
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectUrinary stone disease; Hyperandrogenism; Polycystic ovary syndrome; Combined oral contraceptives
dc.titleIs polycystic ovarian syndrome a risk factor for urolithiasis?
dc.title.alternativeIs polycystic ovarian syndrome a risk factor for urolithiasis
dc.typeLetter

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