Human Immunodeficiency Virus (HIV)-Negative and Human Herpes Virus-8 (HHV-8)-Positive Primary Effusion Lymphoma: A Case Report and Review of the Literature

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dc.authoridBayrak, Reyhan/0000-0001-7450-9828|YALCIN, Kadir Serkan/0000-0002-8028-1070
dc.contributor.authorKaratas, Sonay Guven
dc.contributor.authorBayrak, Reyhan
dc.contributor.authorBalcik, Ozlem Sahin
dc.contributor.authorYalcin, Kadir Serkan
dc.contributor.authorAtici, Esra
dc.contributor.authorAkyildiz, Umit
dc.contributor.authorKosar, Ali
dc.date.accessioned2025-10-24T18:09:59Z
dc.date.available2025-10-24T18:09:59Z
dc.date.issued2013
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractPrimary effusion lymphoma (PEL) is a rare type of non-Hodgkin lymphoma that presents with serosal effusion in body cavities, without obvious tumor masses. Although PEL occurs in immunocompromised patients that are human immunodeficiency virus (HIV) positive, it also occurs in immunocompetent human herpes virus-8 (HHV-8)-positive patients. Herein we present an immunocompetent, HIV-negative, CD-20-negative, HHV-8-positive patient with pleural effusion that was diagnosed as PEL. The CHOP protocol and talc pleurodesis were administered. HHV-8 plays a causative role in PEL and is important for differentiating PEL from other types of lymphoma. As such, in addition to pleurodesis antiviral treatment should be considered for optimal treatment outcome.
dc.identifier.doi10.4274/tjh.53215
dc.identifier.endpage71
dc.identifier.issn1300-7777
dc.identifier.issn1308-5263
dc.identifier.issue1
dc.identifier.pmid24385757
dc.identifier.scopus2-s2.0-84874865514
dc.identifier.scopusqualityQ3
dc.identifier.startpage67
dc.identifier.urihttps://doi.org/10.4274/tjh.53215
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3923
dc.identifier.volume30
dc.identifier.wosWOS:000316239000013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofTurkish Journal Of Hematology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectDifferential diagnosis; Human herpes virus-8; Human immunodeficiency virus (HIV); Pleural effusion; Primary effusion lymphoma
dc.titleHuman Immunodeficiency Virus (HIV)-Negative and Human Herpes Virus-8 (HHV-8)-Positive Primary Effusion Lymphoma: A Case Report and Review of the Literature
dc.title.alternativeHuman immunodeficiency virus (HIV)-negative and human herpes virus-8 (HHV-8)-positive primary effusion lymphoma: A case report and review of the literature
dc.typeReview Article

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