Relationship between oxidant and antioxidant activity in hyperemesis gravidarum

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dc.contributor.authorOnaran, Yuksel
dc.contributor.authorKafali, Hasan
dc.contributor.authorDuvan, Candan Iltemir
dc.contributor.authorKeskin, Esra
dc.contributor.authorCelik, Hakim
dc.contributor.authorErel, Ozcan
dc.date.accessioned2025-10-24T18:09:45Z
dc.date.available2025-10-24T18:09:45Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractObjective: To evaluate oxidant and antioxidant activity in patients with hyperemesis gravidarum (HG) by using serum total antioxidant activity (TAO), total free sulfhydryl (-SH), ceruloplasmin and lipid hydroperoxide (LOOH) levels. Materials and methods: In a cross-sectional trial, blood samples were collected from patients with HG (n = 25) and healthy pregnant women (n = 25) as control group. Serum TAO activities, -SH levels and LOOH levels and ceruloplasmin levels were measured. Results: Serum TAO activity was found to be significantly lower (p = 0.003) in patients with HG compared with controls. However, serum -SH levels, LOOH levels and ceruloplasmin levels did not change significantly in patients with HG compared to controls. Conclusion: Presence of oxidative stress in HG patients depends more on reduced antioxidant activities than increased oxidative stress.
dc.identifier.doi10.3109/14767058.2013.842549
dc.identifier.endpage828
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.issue8
dc.identifier.pmid24041031
dc.identifier.scopus2-s2.0-84898912500
dc.identifier.scopusqualityQ1
dc.identifier.startpage825
dc.identifier.urihttps://doi.org/10.3109/14767058.2013.842549
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3801
dc.identifier.volume27
dc.identifier.wosWOS:000334738800011
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofJournal Of Maternal-Fetal & Neonatal Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectAntioxidant activity; hyperemesis gravidarum; pregnancy
dc.titleRelationship between oxidant and antioxidant activity in hyperemesis gravidarum
dc.typeArticle

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