The circulating alarin level was elevated in infertile women with poor ovarian reserve

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dc.authorid0000-0001-7937-4141en_US
dc.contributor.authorYıldırım, Hakan
dc.contributor.authorGörkem, Ümit
dc.date.accessioned2021-07-13T19:24:35Z
dc.date.available2021-07-13T19:24:35Z
dc.date.issued2021en_US
dc.departmentMTÖ Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: We aimed to reveal the association of serum alarin level with POR status of the infertile women in the present study. Methods: The eligibility criteria for this prospective cross-sectional study included a total of 92 infertile women attending the Hitit University Hospital, and all participant women were categorized into two main groups of ovarian reserve: (i) Poor ovarian reserve (POR) group (n = 40) based on ESHRE consensus and (ii) Control group (NOR) (n = 52). Results: The mean adjusted-ages and BMI values of the NOR and POR groups were statistically comparable (p = .057 and p = .600, respectively). The mean E2, FSH, and LH levels were elevated in the POR group (p < .001, for all). The mean AFC and AMH concentration were significantly reduced in the POR group (p < .001, for both). In addition, there was a significant increase in the serum alarin level in the POR group (p < .001). Pearson's analysis revealed that the mean BMI value of the POR group had a weak and negative correlation (r = 0.318, p = .046). Also, there was no correlation between serum alarin with E2 and FSH levels in both study groups. A weak and positive correlation was found between serum alarin and LH concentration only in the POR group (r = 0.318, p = .045). The mean AMH and AFC values were not significantly correlated with serum alarin levels. Conclusion: The circulating alarin level was significantly elevated in infertile women with POR patterns. In addition, the alarin level was significantly correlated with the serum LH concentration in the POR pattern.en_US
dc.identifier.citationYildirim, E., & Gorkem, U. (2021). The circulating alarin level was elevated in infertile women with poor ovarian reserve. Gynecological Endocrinology, 1-4.en_US
dc.identifier.doi10.1080/09513590.2021.1950683
dc.identifier.endpage4en_US
dc.identifier.issn0951-3590en_US
dc.identifier.issn1473-0766en_US
dc.identifier.pmid34241554
dc.identifier.scopus2-s2.0-85110319351en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://doi.org/10.1080/09513590.2021.1950683
dc.identifier.urihttps://hdl.handle.net/20.500.12899/279
dc.identifier.wosWOS:000671486700001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYıldırım, Hakan
dc.language.isoenen_US
dc.publisherTaylor & Francisen_US
dc.relation.ispartofGynecological Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlarinen_US
dc.subjectLuteinizing hormoneen_US
dc.subjectNormal ovarian reserveen_US
dc.subjectPoor ovarian reserveen_US
dc.titleThe circulating alarin level was elevated in infertile women with poor ovarian reserveen_US
dc.typeArticleen_US

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