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    Influences of Topical Cyclopentolate on Anterior Chamber Parameters With a Dual-Scheimpflug Analyzer in Healthy Children
    (Slack Inc, 2015) Guler, Emre; Guragac, Fatma Betul; Tenlik, Aylin; Yagci, Ramazan; Arslanyilmaz, Zeynel; Balci, Mehmet
    Purpose: To evaluate the changes of anterior segment parameters following the topical instillation of cyclopentolate hydrochloride 1% with the Galilei dual-Scheimpflug analyzer (GSA) (Ziemer Ophthalmology Co., Port, Switzerland) in healthy children. Methods: Fifty children (29 boys, 21 girls) were evaluated before and 60 minutes after instillation of three drops of 1% cyclopentolate hydrochloride using the GSA. The measurements before and after cycloplegia, including anterior chamber depth (ACD), anterior chamber angle (ACA), anterior chamber volume (ACV), central corneal thickness (CCT), and pupil size, were evaluated using the paired t test. Results: The mean age of the patients was 10.27 +/- 3.32 years (range: 5 to 15 years). Measurements between the two sessions were significantly different for all parameters (P < .05), except for CCT (P > .05). Conclusions: The GSA demonstrated a statistically significant increase in ACD, ACV, ACA, and pupil size following the topical application of cyclopentolate hydrochloride 1%. These results should be considered during biometric measurement and refractive surgery planning.
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    Repeatability and Reproducibility of Anterior Segment Measurements in Normal Eyes Using Dual Scheimpflug Analyzer
    (Turkish Ophthalmological Soc, 2015) Altiparmak, Zeynep; Yagci, Ramazan; Guler, Emre; Arslanyilmaz, Zeynel; Canbal, Metin; Hepsen, Ibrahim F.
    Objectives: To assess the repeatability and reproducibility of anterior segment measurements including aberrometric measurements provided by a dual Scheimpflug analyzer (Galilei) system in normal eyes. Materials and Methods: Three repeated consecutive measurements were taken by two independent examiners. The following were evaluated: total corneal power and posterior corneal power, corneal higher-order wavefront aberrations (6.0 mm pupil), pachymetry at the central, paracentral, and peripheral zones, and anterior chamber depth (ACD). Repeatability was assessed by calculating the within subject standard deviation, precision, repeatability, and intraclass correlation coefficient (ICC). Bland-Altman analysis was used for assessing reproducibility. Results: Thirty eyes of 30 patients were included. The best ICC values were for corneal pachymetry and ACD. For both observers, acceptable ICC was also achieved for the other parameters, the only exceptions being posterior corneal astigmatism and total high order aberration. The 95% LoA (Limits of Agreement) values for all measurements showed small variability between the two examiners. Conclusion: The Galilei system provided reliable measurements of anterior segment parameters. Therefore, the instrument can be confidently used for routine clinical use and research purposes.
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    Repeatability and reproducibility of Galilei measurements in normal keratoconic and postrefractive corneas
    (Elsevier Science Bv, 2014) Guler, Emre; Yagci, Ramazan; Akyol, Mesut; Arslanyilmaz, Zeynel; Balci, Mehmet; Hepsen, Ibrahim F.
    Objective: To assess the repeatability and reproducibility of the anterior segment measurements performed with a dual Scheimpflug analyzer (Galilei) in normal, keratoconic and post-refractive surgery corneas. Methods: To evaluate the repeatability, two additional measurements were performed by the first examiner. To assess reproducibility, this was later followed by a single reading by the second examiner. The following parameters were recorded and evaluated in this study; central corneal thickness (CCT), thinnest corneal thickness (TCT), mean total corneal power (TCP) in central (0-4 mm), mean posterior corneal power (PCP) in central (0.5-2 mm), anterior and posterior elevation (best fit sphere [BFS]) in central 8 mm anterior and posterior eccentricity (epsilon(2)) in central 8 mm. Repeatability and reproducibility for each corneal parameter was assessed using the Bland-Altman analysis. Results: Each of the three groups was consisted of 20 subjects (totally 60 patients, 30 men and 30 women). The 95% LoA for repeatability was very small, indicating small discrepancies between measurements related to CCT. Acceptable repeatability was also achieved for the other parameters in each group. However, the 95% LoA for value TCP was larger in keratoconic eyes. The 95% LoA for reproducibility was also very small, and acceptable for all measured parameters in each group. In addition, the 95% LoA was larger for the measurement of CCT and TCT for postrefractive corneas. Conclusions: The anterior segment measurements provided by Galilei showed good repeatability and reproducibility for normal, keratoconic and postrefractive corneas. (C) 2014 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.