Malondialdehyde and nitric oxide levels and catalase, superoxide dismutase, and glutathione peroxidase levels in maternal blood during diferent trimesters of pregnancy and in the cord blood of newborns

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dc.contributor.authorYÜKSEL, Sevda
dc.contributor.authorYİĞİT, AYŞE ARZU
dc.date.accessioned2025-10-24T18:04:28Z
dc.date.available2025-10-24T18:04:28Z
dc.date.issued2015
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractBackground/aim: To determine whether levels of malondialdehyde (MDA), nitric oxide (NO), superoxide dismutase (SOD), glutathioneperoxidase (GPx), and catalase (CAT) change during the 3 trimesters of pregnancy, and to compare the third trimester of pregnancywith newborn cord blood in respect to the levels of MDA, NO, and antioxidant enzymes.Materials and methods: Maternal blood samples were collected at 9 13, 22 26, and 36 40 weeks of gestation. Cord blood was collectedat the time of delivery.Results: NO levels and GPx activity were higher in the second and third trimesters than in the frst trimester. MDA level was lower in thethird trimester and SOD and CAT activities were lower in the second and third trimesters than the frst trimester. In cord blood, MDAand NO levels were lower while CAT and GPx activities were higher than in the third trimester of pregnancy.Conclusion: Tese results suggest that the balance of free radical and antioxidant production during pregnancy ensures healthy fetusgrowth and development.
dc.identifier.endpage459
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue2
dc.identifier.startpage454
dc.identifier.trdizinid171071
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/171071
dc.identifier.urihttps://hdl.handle.net/20.500.12899/2888
dc.identifier.volume45
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzTR-Dizin_20251023
dc.subjectBiyokimya ve Moleküler Biyoloji
dc.titleMalondialdehyde and nitric oxide levels and catalase, superoxide dismutase, and glutathione peroxidase levels in maternal blood during diferent trimesters of pregnancy and in the cord blood of newborns
dc.typeArticle

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