Misdiagnosis of macroamylasemia in pregnancy as pancreatitis

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dc.authoridakgun, nilufer/0000-0003-0414-9470
dc.contributor.authorEser, Ayla
dc.contributor.authorAkgun, Nilufer
dc.contributor.authorYuce, Ebru
dc.contributor.authorKafali, Hasan
dc.date.accessioned2025-10-24T18:09:36Z
dc.date.available2025-10-24T18:09:36Z
dc.date.issued2015
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractBackground: While elevated serum amylase in the presence of abdominal pain can be indicative of pancreatitis, differential diagnosis of macroamylasemia depends on additional assessment of serum lipase and urinary amylase. The present report concerns misdiagnosis of pancreatitis in a pregnant woman with elevated serum amylase but normal lipase. Highlights: The patient was a nulligravid woman on her first pregnancy diagnosed with pancreatitis in her 32nd week plus 3 days of gestation, on the basis of elevated serum amylase and abdominal pain, after treatment for premature contractions and antepartum vaginal bleeding with ritodrine HCl and nifedipine. She was started on painful and invasive intravenous hydration; oral intake was stopped. Repeat elevated serum amylase suggested that the patient might in fact have macroamylasemia, not pancreatitis. Conclusions: Normal serum lipase levels should be considered as a likely indication of an alternative cause of elevated serum amylase to pancreatitis, and urinary amylase should be routinely checked to assist in differential diagnosis to avoid unnecessary and invasive treatment and stress to pregnant women.
dc.identifier.doi10.1515/crpm-2015-0016
dc.identifier.endpage95
dc.identifier.issn2192-8959
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85042575368
dc.identifier.scopusqualityN/A
dc.identifier.startpage93
dc.identifier.urihttps://doi.org/10.1515/crpm-2015-0016
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3733
dc.identifier.volume4
dc.identifier.wosWOS:000422597700004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWalter De Gruyter Gmbh
dc.relation.ispartofCase Reports In Perinatal Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectAmylase; macroamylasemia; pancreatitis; pregnancy
dc.titleMisdiagnosis of macroamylasemia in pregnancy as pancreatitis
dc.typeArticle

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