Caffeic acid phenethyl ester as a remedial agent for reproductive functions and oxidative stress-based pathologies of gonads

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dc.contributor.authorAkyol, Sumeyya
dc.contributor.authorAkbas, Ali
dc.contributor.authorButun, Ilknur
dc.contributor.authorToktas, Muhsin
dc.contributor.authorOzyurt, Huseyin
dc.contributor.authorSahin, Semsettin
dc.contributor.authorAkyol, Omer
dc.date.accessioned2025-10-24T18:10:09Z
dc.date.available2025-10-24T18:10:09Z
dc.date.issued2015
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractIn recent years, the studies on the roles of caffeic acid phenethyl ester (CAPE) in several disease models and cell cultures are tremendously growing. It is such a great molecule that was used by ancient times to ameliorate some diseases and nowadays, it is used by modern medicine to test the effectiveness. In this mini-review article, the protection capability of CAPE, as a liposoluble antioxidant and a potent nuclear factor kappa B inhibitor, on oxidative and non-oxidative ovary, and testis damages has been summarized. In view of our laboratory findings/experience and those reported in the hitherto literature, we suggest that CAPE possesses protective effects for pathologies of the reproductive organs induced by untoward effects of harmful molecules such as free oxygen radicals, pesticides, methotrexate, and MK-801 (dizocilpine).
dc.identifier.doi10.5455/jice.20150402062823
dc.identifier.endpage191
dc.identifier.issn2146-8397
dc.identifier.issue2
dc.identifier.pmid26401405
dc.identifier.startpage187
dc.identifier.urihttps://doi.org/10.5455/jice.20150402062823
dc.identifier.urihttps://hdl.handle.net/20.500.12899/4013
dc.identifier.volume4
dc.identifier.wosWOS:000361218800014
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherEjmanager Llc
dc.relation.ispartofJournal Of Intercultural Ethnopharmacology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectCaffeic acid phenethyl ester; gonads; ovary; oxidative damage; protection; testis
dc.titleCaffeic acid phenethyl ester as a remedial agent for reproductive functions and oxidative stress-based pathologies of gonads
dc.typeArticle

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