Effect of Underlying Infertility Factors on Second Trimester Serum Screening Results

Küçük Resim Yok

Tarih

2014

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Sci Printers & Publ Inc

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

OBJECTIVE: To determine whether assisted reproductive technologies (ART) alone or an underlying cause of infertility has any effect on second trimester serum screening results. STUDY DESIGN: Second trimester serum screening results of ART pregnancies of women with polycystic ovary syndrome (IVF-P group) were compared with those of women who underwent ART dike to male factor infertility (IVF-M group) and of women who conceived spontaneously. RESULTS: Comparison of the groups for a-fetoprotein, beta-hCG, and beta-hCG multiples of the median (MoM) revealed a significant difference between the IVF-M and control groups. Comparison of groups for unconjugated estriol (uE(3)) and uE(3) MoM levels revealed a statistically significant difference between the IVF-P versus the control groups. CONCLUSION: It seems advisable to use a population of ART pregnancies, preferably divided by type of treatment and the etiology of the infertility, when establishing median curves for second trimester serum screening markers.

Açıklama

Anahtar Kelimeler

alpha-fetoprotein; human; Down's syndrome; estriol; HCG-beta; infertility; polycystic ovary syndrome; reproductive technology; assisted; screening; second trimester screening

Kaynak

Journal Of Reproductive Medicine

WoS Q Değeri

Q4

Scopus Q Değeri

Cilt

59

Sayı

1-2

Künye