Determination of Intestinal Enzyme Activities During Infancy Period

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dc.authoridYALCIN, Siddika Songul/0000-0001-9061-4281;
dc.contributor.authorOrun, Emel
dc.contributor.authorYalcin, Songul
dc.contributor.authorLay, Incilay
dc.contributor.authorDursun, Arzu
dc.contributor.authorOzkara, Asuman
dc.date.accessioned2025-10-24T18:09:58Z
dc.date.available2025-10-24T18:09:58Z
dc.date.issued2016
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractIntroduction: Intestinal enzyme activities are indirect indicators that reflect the existence and metabolic activity of bacteria living in the intestinal flora. The purpose of the study was to measure fecal beta (beta)-glucuronidase, beta-glucosidase and urease enzyme activities and to determine the factors that affect levels in 6 week old and 8 month old babies. Materials and Methods: The study comprised 100 healthy infants at 6 weeks of age. Feces samples were collected from all infants. However, 17 of the feces samples were not included due to the lack of particles in the feces. The same samples were also taken from 35 infants at 8 months of age. Twenty-five of the infants had given feces samples at both 6 weeks and 8 months of age. Urease, beta-glucuronidase and beta-glucosidase enzyme activities (nmol/min-1/mg-protein-1) were measured. Results: In repeated measures, the levels of beta-glucuronidase and urease declined over time and beta-glucosidase levels increased. At 8 months of age, higher beta-glucuronidase levels were obtained in premature infants. At 6 weeks of age, lower levels of urease were measured in babies who were started breastfeeding at the first hour of life and were bottle-fed. Exclusive breastfeeding had no influence on the intestinal enzyme activities. Conclusions: In early infancy period when microflora is structured, intestinal enzyme activities are important that show indirectly functionality of the microflora. However, it is difficult to highlight what affects the levels of intestinal enzymes because activities vary according to the age.
dc.identifier.doi10.4274/jcp.43434
dc.identifier.endpage59
dc.identifier.issn1304-9054
dc.identifier.issn1308-6308
dc.identifier.issue2
dc.identifier.scopus2-s2.0-84978696179
dc.identifier.scopusqualityQ4
dc.identifier.startpage53
dc.identifier.urihttps://doi.org/10.4274/jcp.43434
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3909
dc.identifier.volume14
dc.identifier.wosWOS:000407729200002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isotr
dc.publisherGalenos Yayincilik
dc.relation.ispartofGuncel Pediatri-Journal Of Current Pediatrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectIntestinal enzyme activity; urease; beta-glucuronidase; beta-glucosidase
dc.titleDetermination of Intestinal Enzyme Activities During Infancy Period
dc.title.alternativeDetermination of intestinal enzyme activities during infancy period
dc.typeArticle

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