Effect of underlying infertility factors on second trimester serum screening results

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dc.contributor.authorKöşüş, Nermin
dc.contributor.authorKoşus, Aydin
dc.contributor.authorDuran, Müzeyyen
dc.contributor.authorTurhan, Nilgün Öztürk
dc.date.accessioned2025-10-24T18:06:51Z
dc.date.available2025-10-24T18:06:51Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractObjective:To determine whether assisted reproductive technologies (ART) alone or an underlying cause of infertility has any effect on second trimester serum screening results. Study Design: Second trimester serum screening results of ART pregnancies of women with polycystic ovary syndrome (IVF-P group) were compared with those of women who underwent ART due to male factor infertility (IVF-M group) and of women who conceived spontaneously. Results: Comparison of the groups for ?-fetoprotein, ?-hCG, and ?-hCG multiples of the median (MoM) revealed a significant difference between the IVF-M and control groups. Comparison of groups for unconjugated estriol (uE<inf>3</inf>) and uE<inf>3</inf> MoM levels revealed a statistically significant difference between the IVF-P versus the control groups. Conclusion: It seems advisable to use a population of ART pregnancies, preferably divided by type of treatment and the etiology of the infertility, when establishing median curves for second trimester serum screening markers. © Journal of Reproductive Medicine®, Inc. © 2014 Elsevier B.V., All rights reserved.
dc.identifier.endpage80
dc.identifier.issn0024-7758
dc.identifier.issue1-2
dc.identifier.pmid24597291
dc.identifier.scopus2-s2.0-84892881639
dc.identifier.scopusqualityN/A
dc.identifier.startpage76
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3234
dc.identifier.volume59
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.relation.ispartofJournal of Reproductive Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzScopus_20251023
dc.subjectAlpha-fetoprotein
dc.subjectAssisted
dc.subjectDown's syndrome
dc.subjectEstriol
dc.subjectHCG-beta
dc.subjectHuman
dc.subjectInfertility
dc.subjectPolycystic ovary syndrome
dc.subjectReproductive technology
dc.subjectScreening
dc.subjectSecond trimester screening
dc.titleEffect of underlying infertility factors on second trimester serum screening results
dc.typeArticle

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