Predictive Factors of Postoperative Pancreatic Fistula in Geriatric Patients Undergoing Pancreatoduodenectomy for Periampullary Malignancy

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dc.contributor.authorCeylan, Cengiz
dc.contributor.authorKocaaslan, Huseyin
dc.contributor.authorBaran, Necip Tolga
dc.contributor.authorKulus, Mehmet
dc.contributor.authorSaglam, Kutay
dc.contributor.authorAydin, Cemalettin
dc.date.accessioned2025-10-24T18:09:40Z
dc.date.available2025-10-24T18:09:40Z
dc.date.issued2023
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractObjective: To identify predictive factors associated with the occurrence of postoperative pancreatic fistula (POPF) following pancreato-duodenectomy (PD) in an increasingly geriatric population.Study Design: Observational study.Place and Duration of the Study: Department of General Surgery, Inonu University, Malatya, Turkey, from January 2010 to April 2022.Methodology: Demographic and clinicopathological data of 74 geriatric patients who underwent PD for periampullary tumours in the clinic at Inonu University were retrieved from the patient database. POPF was defined and categorised based on the guidelines established by the International Study Group for Pancreatic Surgery (ISGPS). The patients were stratified into two cohorts of POPF and no POPF. Univariate and multivariate analyses were conducted to compare variables between the two groups.Results: The median age of the patient population was 72 (65-92) years, and 51 (68.9%) individuals were male. Among the 74 patients, 35 (47.3%) experienced POPF. In the multivariate analysis, hypertension (HT, p=0.012), Wirsung diameter <3.5 mm (p<0.01), and pancreaticojejunostomy (PJ, p=0.022) emerged as independent risk factors for POPF.Conclusion: In the context of geriatric patients undergoing PD, HT, intraoperative wirsung diameter <3.5 mm, and PJ were identified as independent risk factors for POPF. These findings can guide the adoption of safer techniques in preoperative and intraoperative evaluations, as well as in postoperative follow-ups of patients presenting with these risk factors.
dc.identifier.doi10.29271/jcpsp.2023.12.1439
dc.identifier.endpage1444
dc.identifier.issn1022-386X
dc.identifier.issn1681-7168
dc.identifier.issue12
dc.identifier.pmid38062603
dc.identifier.startpage1439
dc.identifier.urihttps://doi.org/10.29271/jcpsp.2023.12.1439
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3772
dc.identifier.volume33
dc.identifier.wosWOS:001117798400016
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherColl Physicians & Surgeons Pakistan
dc.relation.ispartofJcpsp-Journal Of The College Of Physicians And Surgeons Pakistan
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectElderly; Anastomotic leakage; Predictive factor; Postoperative pancreatic fistula; Pancreatoduodenectomy
dc.titlePredictive Factors of Postoperative Pancreatic Fistula in Geriatric Patients Undergoing Pancreatoduodenectomy for Periampullary Malignancy
dc.typeArticle

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