An investigation of histopathologic and morphometric effect of black carrot juice on acrylamid induced neurotoxicity

Basit Öğe Kaydı
dc.authorid0000-0002-4916-7675en_US
dc.contributor.authorEsen, Gülru
dc.contributor.authorUçkun, Miraç
dc.contributor.authorÖzkaya, Ahmet
dc.contributor.authorYoloğlu, Ertan
dc.contributor.authorAnnaç, Ebru Elibol
dc.contributor.authorPekmez, Hıdır
dc.contributor.authorUludağ, Seda
dc.date.accessioned2021-05-24T08:01:50Z
dc.date.available2021-05-24T08:01:50Z
dc.date.issued2021en_US
dc.departmentMTÖ Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractAcrylamide is an organic compound that is known to have neurotoxic influences. People have high exposure to its impacts because of its extensive uses in the industrial fields and its occurrence in foods. This situation has induced the scientific word to identify naturel components that may eliminate these neurotoxic effects. In this experimental study the influence of black carrot juice containing bioavailable flavonoids was researched on acrylamide neurotoxicity. In the study, laboratory rats were divided in to four groups. Group 1 rats were the control group. While the rats in Group 2 were administered acrylamide substance, the rats in Group 3 were supplemented with black carrot juice + acrylamide, and the rats in Group 4 were given black carrots juice only. At the experiment’s end, biochemical, histopathological, and histomorphometry analysis were performed on exanguned rats. Significant histopathological degenerations were observed in the acrylamide treated group. Despite a volumetric degrease in all brain regions examined histomorphometrically, this decrease was not statistically significant. The malondialdehyde and Glutathione S-transferase levels of the acrylamide group showed a significant increase compared to the control group. The glutathione, carboxylesterase and acetylcholinesterase levels were observed to increase in the acrylamide and black carrot applied group, compared to the acrylamide group. This study’s findings have revealed the black carrot’s healing effects on acrylamide neurotoxicity.en_US
dc.identifier.citationEsen, G., Uçkun, M., Özkaya, A., Yoloğlu, E., Annaç, E., Pekmez, H., Uludağ, S. (2021). An investigation of histopathologic and morphometric effect of black carrot juice on acrylamid induced neurotoxicity . Journal of Experimental and Clinical Medicine, 38 (2), 82-87. Retrieved from https://dergipark.org.tr/en/pub/omujecm/issue/61150/845744en_US
dc.identifier.doi10.52142/omujecm.38.2.5
dc.identifier.endpage87en_US
dc.identifier.issn1309-4483en_US
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85105335447en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage82en_US
dc.identifier.urihttps://doi.org/10.52142/omujecm.38.2.5
dc.identifier.urihttps://dergipark.org.tr/en/pub/omujecm/issue/61150/845744
dc.identifier.urihttps://hdl.handle.net/20.500.12899/144
dc.identifier.volume38en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorPekmez, Hıdır
dc.language.isoenen_US
dc.publisherOndokuz Mayıs Universityen_US
dc.relation.ispartofJournal of Experimental and Clinical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcrylamideen_US
dc.subjectNeurotoxicityen_US
dc.subjectBlack Carroten_US
dc.subjectHistopathologyen_US
dc.subjectMorphometryen_US
dc.titleAn investigation of histopathologic and morphometric effect of black carrot juice on acrylamid induced neurotoxicityen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Gülru ESEN-Makale Dosyası.pdf
Boyut:
1.96 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Temel Tıp Bilimleri Bölümü Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu