Uremic pruritus and its relationship with geriatric syndromes in older hemodialysis patients: analysis using the 5-D itch scale

Basit Öğe Kaydı
dc.contributor.authorYakaryilmaz, Funda Datli
dc.contributor.authorTurkmen, Dursun
dc.contributor.authorBerktas, Haci Bayram
dc.contributor.authorPembegul, Irem
dc.date.accessioned2026-06-19T06:31:56Z
dc.date.available2026-06-19T06:31:56Z
dc.date.issued2026
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractBackground: Uremic pruritus (UP) is a common and distressing symptom in hemodialysis patients and may contribute to geriatric syndromes such as impaired sleep, depression, cognitive decline, and functional limitation. Evidence focusing on comprehensive geriatric assessment in older hemodialysis populations remains limited. Objectives: To evaluate the association between UP severity (5-D Itch Scale) and geriatric syndromes (functional status, cognitive function, depressive symptoms, nutritional status, and sleep quality) in older hemodialysis patients. Methods: This cross-sectional study included patients aged ≥65 years who had undergone hemodialysis for at least 6 months. UP was assessed using the 5-D Itch Scale. Comprehensive geriatric assessment comprised Activity of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), Mini-Mental State Examination (MMSE), Geriatric Depression Scale–15 (GDS-15), Mini Nutritional Assessment–Short Form (MNA-SF), and Pittsburgh Sleep Quality Index (PSQI). Group comparisons were performed using nonparametric tests, and associations were examined using Spearman correlation. Results: A total of 118 older hemodialysis patients were included; 70.4% (n = 83) reported UP. Vitamin D levels were lower in patients with UP. Compared with patients without UP, those with UP had lower MMSE scores, and higher GDS and PSQI scores. 5-D score correlated positively with age, depressive symptoms, sleep disturbance, and ADL dependency; and negatively with dialysis duration and cognitive function. Conclusions: In older hemodialysis patients, UP is common and is associated with worse sleep quality, more depressive symptoms, lower cognitive performance, and greater functional limitation. Integrating UP screening into routine geriatric assessment may help identify vulnerable patients and guide multidisciplinary symptom management strategies. © 2026 Informa UK Limited, trading as Taylor & Francis Group.
dc.identifier.doi10.1080/15569527.2026.2656174
dc.identifier.issn1556-9527
dc.identifier.pmid41964296
dc.identifier.scopus2-s2.0-105035799640
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1080/15569527.2026.2656174
dc.identifier.urihttps://hdl.handle.net/20.500.12899/4870
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor and Francis Ltd.
dc.relation.ispartofCutaneous and Ocular Toxicology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20260612
dc.subject5-D Itch Scale
dc.subjectCognition
dc.subjectDepression
dc.subjectHemodialysis
dc.subjectOlder Adults
dc.subjectSleep Quality
dc.subjectUremic Pruritus
dc.titleUremic pruritus and its relationship with geriatric syndromes in older hemodialysis patients: analysis using the 5-D itch scale
dc.typeArticle

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu