Synthesis and biological activities of new hybrid chalcones with benzoic acid ring
Küçük Resim Yok
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
A series of E-4-(3-oxo-3-(substituted)prop-1-en-1-yl)benzoic acid derivatives (1-5) were synthesized by the Claisen-Schmidt condensation of various ketones with 4-formylbenzoic acid. The anticholinesterase (AChE and BChE), tyrosinase, and urease inhibition activities of the synthesized compounds (1-5) were examined. It was found that the most active compound against AChE enzyme in anticholinesterase inhibition activity was compound 1. Compound 4 was the most active compound in tyrosinase inhibition activity, while compound 3 was the most active compound in urease psychological activity.
Açıklama
Anahtar Kelimeler
Kimya, Organik, Biyokimya ve Moleküler Biyoloji, Chalcone, Urease inhibitory activity, Anticholinesterase activity, Tyrosinase inhibitory activity
Kaynak
International Journal of Chemistry and Technology (IJCT)
WoS Q Değeri
Scopus Q Değeri
Cilt
6
Sayı
1
