Effect of One Unit Blood Donation on Appetite-Related Biomarkers

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dc.contributor.authorErdamar, Husamettin
dc.contributor.authorCakmak, Muzaffer
dc.date.accessioned2025-10-24T18:10:21Z
dc.date.available2025-10-24T18:10:21Z
dc.date.issued2016
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractPurpose: It is commonly reported that blood donation (BD) leads to an increase in appetite. To investigate this claim, a questionnaire was offered to 306 people who had a history of BD at least once in their life. Following a positive outcome from the questionnaire, we further investigated the impact of BD on appetite. Materials and Methods: The questionnaire study consists of a 5-question survey with VAS was performed on 399 volunteers. Later, 108 volunteers were enrolled in a laboratory study. Blood samples were withdrawn before and after BD. Leptin, ghrelin, neuropeptide-Y (NPY), and alpha-melanocyte stimulating hormone (alpha-MSH) levels were measured by ELISA kits. VAS assessment was also performed on all participants before and after BD. Results: There was a significant decrease in the level of leptin but the levels of ghrelin, NPY and a- MSH were unchanged. A significant change in VAS value in terms of appetite was also observed. Conclusion: The elevation of appetite after BD is predominantly psychological. Hormonal changes may contribute to the control of hypothalamic hunger and satiety centers.
dc.identifier.endpageS94
dc.identifier.issn0147-958X
dc.identifier.issn1488-2353
dc.identifier.issue6
dc.identifier.scopus2-s2.0-85047589845
dc.identifier.scopusqualityQ2
dc.identifier.startpageS89
dc.identifier.urihttps://hdl.handle.net/20.500.12899/4123
dc.identifier.volume39
dc.identifier.wosWOS:000389725000019
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherCanadian Soc Clinical Investigation
dc.relation.ispartofClinical And Investigative Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectGhrelin Levels; Iron Stores; Donors; Receptor; Phlebotomy; Reduction; Hormones; Release; Leptin; Trial
dc.titleEffect of One Unit Blood Donation on Appetite-Related Biomarkers
dc.typeArticle

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