Interaction of nickel ferrite nanoparticles with nucleic acids

Basit Öğe Kaydı
dc.contributor.authorTopkaya, Seda Nur
dc.contributor.authorKaya, Hüseyin Oğuzhan
dc.contributor.authorÖzcan, İmren
dc.contributor.authorKöytepe, Süleyman
dc.contributor.authorE.Cetin, Arif
dc.date.accessioned2022-03-03T12:28:49Z
dc.date.available2022-03-03T12:28:49Z
dc.date.issued2022en_US
dc.departmentMTÖ Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Biyomühendislik Bölümüen_US
dc.description.abstractIn this article, we introduced an electrochemical biosensor employing graphite electrodes (GE) decorated with Nickel ferrite (NiFe2O4) nanoparticles for nucleic acid detection. NiFe2O4 nanoparticles in a narrow size distribution were synthesized with co-precipitation technique. Their chemical and crystallographic properties were characterized with FTIR and X-ray spectroscopies. Nanoparticle size distribution and hydrodynamic diameter were determined with particle size analyzer. Elemental content and purity of nanoparticles were analyzed with EDX analysis. Our analyses showed a diameter of ~10 nm for NiFe2O4 nanoparticles. Electrochemical properties of NiFe2O4 nanoparticles were examined with different analysis methods. Conductivity properties of NiFe2O4 nanoparticles were investigated with Cyclic Voltammetry (CV), which confirmed that nanoparticles on GE surface have a high surface area and conductivity. More importantly, in this article, the interactions between NiFe2O4 nanoparticles and double stranded DNA (dsDNA), single stranded DNA (ssDNA), and RNA were for the first time examined using Differential Pulse Voltammetry (DPV), CV, and Electrochemical Impedance Spectroscopy (EIS). Oxidation peak currents of NiFe2O4 nanoparticles and guanine bases of dsDNA, ssDNA, and RNA showed that NiFe2O4 nanoparticles effectively interacts with nucleic acids via an electrostatic mode.en_US
dc.identifier.citationKaraca Açarı, İdil,(2022), Interaction of nickel ferrite nanoparticles with nucleic acids, Malatya Turgut Özal Üniversitesi, Elsevier B.V.en_US
dc.identifier.doi10.1016/j.colsurfb.2021.112282
dc.identifier.endpage8en_US
dc.identifier.issue112282en_US
dc.identifier.pmid34915301
dc.identifier.scopus2-s2.0-85121231324en_US
dc.identifier.startpage2en_US
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/34915301/
dc.identifier.urihttps://hdl.handle.net/20.500.12899/527
dc.identifier.volume211en_US
dc.identifier.wosWOS:000734888800005en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKaraca Açarı, İdil
dc.language.isoenen_US
dc.publisherElsevier B.V.en_US
dc.relation.ispartofColloids Surf B Biointerfacesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCo-precipitation; Differential pulse voltammetry; Electrochemical impedance spectroscopy; NiFe(2)O(4) nanoparticles; Nickel ferrite.en_US
dc.titleInteraction of nickel ferrite nanoparticles with nucleic acidsen_US
dc.typeArticleen_US

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