The association between serum follicle-stimulating hormone levels and the success of microdissection testicular sperm extraction in patients with azoospermia

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dc.contributor.authorYıldırım, Mehmet Erol
dc.contributor.authorKoç, Akif
dc.contributor.authorKaygusuz, İkbal Cekmen
dc.contributor.authorBadem, Hüseyin
dc.contributor.authorKarataş, Ömer Faruk
dc.contributor.authorÇimentepe, Ersin In
dc.contributor.authorÜnal, Doğan
dc.date.accessioned2025-10-24T18:06:53Z
dc.date.available2025-10-24T18:06:53Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractPurpose: To evaluate the predictive power of luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, testicular biopsy histology and male age were evaluated with respect to the success of sperm retrieval in a microdissection testicular sperm extraction (microTESE) procedure, pregnancy and live birth rates. Materials and Methods: We examined the data of 131 infertile men with non-obstructive azoospermia, who have undergone microTESE operation. The men were classified into two groups based on serum follicle-stimulating hormone (FSH) levels ? 15 mIU/mL (group 1) and > 15 mIU/mL (group 2). Results: Group 1 consisted of 59 patients (mean age 36.2 ± 6.2 years) and group 2 consisted of 72 (mean age 38.8 ± 7.4 years) patients. Sperm retrieval and pregnancy rates were 66.1% and 16.9% in normal FSH group, respectively. These parameters were higher than those of men with FSH > 15 (43% and 8.3%, respectively). Only 128 patients had histopathological diagnosis. Sperm was retrieved from 12/30 (40%) patients with maturation arrest, 9/29 (31.03%) patients with seminiferous tubules atrophy, 14/40 (35%) patients with sertoli cell only syndrome and 13/13 (100%) of patients with hypospermatogenesis. There was no statistically significant difference in pathological diagnosis between pregnancy and live birth rates. Conclusion: These results demonstrate that there is a significant difference with sperm retrieval, pregnancy rates and live birth rates comparing the FSH levels. Histopathological findings did not associate with successful microTESE, pregnancy rates and live birth rates. © 2015 Elsevier B.V., All rights reserved.
dc.identifier.endpage1828
dc.identifier.issn1735-546X
dc.identifier.issn1735-1308
dc.identifier.issue4
dc.identifier.pmid25194084
dc.identifier.scopus2-s2.0-84906959542
dc.identifier.scopusqualityQ3
dc.identifier.startpage1825
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3264
dc.identifier.volume11
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherUrology and Nephrology Research Centre info@unrc.ir
dc.relation.ispartofUrology Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzScopus_20251023
dc.subjectAzoospermia
dc.subjectInfertility
dc.subjectMale
dc.subjectMicrodissection
dc.subjectSperm retrieval
dc.subjectSpermatogenesis
dc.subjectTesticular diseases
dc.titleThe association between serum follicle-stimulating hormone levels and the success of microdissection testicular sperm extraction in patients with azoospermia
dc.typeArticle

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