Electrophysiological subtypes and prognostic factors of childhood Guillain-Barré syndrome

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dc.contributor.authorKonuşkan, Bahadir
dc.contributor.authorOkuyaz, Çetin
dc.contributor.authorTaşdelen, Bahar
dc.contributor.authorHiz Kurul, Semra
dc.contributor.authorAnlar, Banu
dc.contributor.authorKöse, Gülşen
dc.contributor.authorTan, Huseyin
dc.date.accessioned2025-10-24T18:06:46Z
dc.date.available2025-10-24T18:06:46Z
dc.date.issued2018
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractIntroduction: We assessed the clinical, epidemiologic, electrophysiological and prognostic characteristics of childhood Guillain-Barré Syndrome admitted to 13 pediatric neurology centers in Turkey. Method: Using a standard data recording form age, sex, duration of symptoms, distribution of weakness at onset, cranial nerve involvement, cerebrospinal fluid findings, electrophysiological findings, duration of hospitalization, requirement of ventilation, treatment and clinical evaluation scale at onset, discharge and 1, 3, 6, and 12 months after discharge were recorded. Results: Among the 236 children with a median age of 6.8 years there was a male to female ratio of 1.3. Based on the electrophysiological features; 84 patients were classified as acute inflammatory demyelinating polyrediculoneuropathy (AIDP), 61 as acute motor axonal neuropathy (AMAN), 21 as acute motor-sensory axonal neuropathy (AMSAN). The incidence of cranial nerve involvement was 16%, and was related to lower clinical scores at discharge and 6 months after discharge. Clinical scale scores between axonal and demyelinating subgroups did not show statistically significant difference except for admission (p<0.05). Conclusion: Electrophysiological subtypes are not important in prognosis in our series. However, duration of weakness, duration of hospitalization and ventilation requirement can affect prognosis negatively. © 2018 Elsevier B.V., All rights reserved.
dc.identifier.doi10.5152/npa.2017.16996
dc.identifier.endpage204
dc.identifier.issn1300-0667
dc.identifier.issn1309-4866
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85056507169
dc.identifier.scopusqualityN/A
dc.identifier.startpage199
dc.identifier.urihttps://doi.rog/10.5152/npa.2017.16996
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3198
dc.identifier.volume55
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTurkish Neuropsychiatric Society atbasoglu@gmail.com
dc.relation.ispartofNoropsikiyatri Arsivi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzScopus_20251023
dc.subjectChildhood
dc.subjectElectroneuromyography
dc.subjectGuillain-Barré syndrome
dc.titleElectrophysiological subtypes and prognostic factors of childhood Guillain-Barré syndrome
dc.typeArticle

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