Oncogenes and tumor suppressor genes as a biomarker in breast cancer

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dc.contributor.authorÜçtepe, Eyyüp
dc.contributor.authorAcar, Muradiye
dc.contributor.authorGündüz, Esra
dc.contributor.authorGündüz, Mehmet
dc.date.accessioned2025-10-24T18:06:40Z
dc.date.available2025-10-24T18:06:40Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractBreast cancer is the most common cause of cancer in women in the United States and the Western world. The important question is what can be done to limit the human suffering associated with cancer and to reduce the burden on society? One solution is early detection. Early diagnosis of breast cancer before symptoms emerge is the most effective prevention of breast cancer. Currently, mammography is the gold standard for breast cancer screening. The procedure is suggested and often reimbursed for women between the ages of 50 and 75. Yet it is presumed that between 15 and 25 % of women with early-stage breast cancers are presently missed by commonly used diagnostic procedures such as mammography. Since breast cancer is also diagnosed in an increasing number of younger women, the screening strategy should be modified. Hence, oncogenes and tumor suppressor genes could be used as biomarkers for early detection of breast cancer. Eventually, researchers aim to use the molecular data collected from an individual tumor for prognostication and personalized therapy for each patient. Genetic profiles of tumors are now providing information about clinical outcome, and some prognostic and predictive indicators have appeared based on this research. In the near future, prospective tissue collection for molecular analysis may become routine in order to classify patients for alternative treatment options and to optimize treatment strategies based on molecular structure of the cancer. © 2015 Elsevier B.V., All rights reserved.
dc.identifier.doi10.1007/978-81-322-0843-3_3
dc.identifier.endpage51
dc.identifier.isbn8132208420
dc.identifier.isbn9788132208426
dc.identifier.isbn9788132208433
dc.identifier.scopus2-s2.0-84930699274
dc.identifier.scopusqualityN/A
dc.identifier.startpage41
dc.identifier.urihttps://doi.rog/10.1007/978-81-322-0843-3_3
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3120
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSpringer India
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzScopus_20251023
dc.subjectBiomarker
dc.subjectBreast Cancer
dc.subjectEarly Diagnosis
dc.subjectOncogenes
dc.subjectTumor Suppressor Genes
dc.titleOncogenes and tumor suppressor genes as a biomarker in breast cancer
dc.typeBook Chapter

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