The specificity and sensitivity results of the rapid antigen test used in the diagnosis of group A beta hemolytic streptococcal tonsillopharyngitis

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dc.contributor.authorAltun, Hatice Uludağ
dc.contributor.authorMeral, Tuba
dc.contributor.authorArıbaş, Emel Türk
dc.date.accessioned2025-10-24T18:06:53Z
dc.date.available2025-10-24T18:06:53Z
dc.date.issued2015
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractAims: The rapid antigen detection test and throat culture can be used for the diagnosis of group A beta hemolytic streptococcus (GABHS) infections. The aim of this study was to determine the sensitivity and specificity ratios of the rapid antigen test for GABHS in the laboratory setting. Materials and methods: In this study, the throat culture and rapid antigen test results were evaluated for 5120 patients between the ages of 0-18 years, who were admitted between January and June 2014 to the pediatric outpatient clinic with a diagnosis of clinical exudative tonsillopharyngitis. The tests of these patients were performed at the microbiology laboratory of Turgut Ozal University Hospital. Patients with only a throat culture or a rapid antigen test result were excluded from the study. Thus, 1243 patients were included in the current study, in which both tests had been performed. Two throat swab samples were collected from these patients. Culture tests and rapid antigen tests were both performed for the patient samples. The Strep A Abon kit [Hangzhou, China] was used as the rapid antigen test. Results: Nine hundred thirty-six patients had no bacterial growth in their throat cultures, while 307 throat cultures were positive for GABHS. The sensitivity and specificity of the rapid antigen test were 73% and 96.8%, respectively. The positive and negative predictive values for the rapid antigen test were 88.2% and 91.6%, respectively. Conclusion: Although the specificity of the rapid antigen test used in this study was high (96.8%), its sensitivity was determined to be lower (73%). Therefore, for patients in whom negative test results are obtained, it would be appropriate to confirm the test results with throat cultures. © 2020 Elsevier B.V., All rights reserved.
dc.identifier.endpage290
dc.identifier.issn2283-9720
dc.identifier.issn0393-6384
dc.identifier.issue2
dc.identifier.scopus2-s2.0-84944275324
dc.identifier.scopusqualityN/A
dc.identifier.startpage287
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3271
dc.identifier.volume31
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherActa Medica Mediterranea
dc.relation.ispartofActa Medica Mediterranea
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzScopus_20251023
dc.subjectGroup A beta hemolytic streptococcus
dc.subjectRapid antigen test
dc.subjectSensitivity
dc.subjectSpecificity
dc.subjectTonsillopharyngitis
dc.titleThe specificity and sensitivity results of the rapid antigen test used in the diagnosis of group A beta hemolytic streptococcal tonsillopharyngitis
dc.typeArticle

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