Importance of Labarotory Parameters in Obstructive Sleep Apnea

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dc.authoridFIRAT, Hikmet/0000-0003-2594-4887;
dc.contributor.authorErsoy, Ebru Ortac
dc.contributor.authorYuce, Gulbahar Darilmaz
dc.contributor.authorDuru, Serap
dc.contributor.authorFirat, Hikmet
dc.contributor.authorArdic, Sadik
dc.contributor.authorKurt, Bahar
dc.date.accessioned2025-10-24T18:09:58Z
dc.date.available2025-10-24T18:09:58Z
dc.date.issued2016
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractObjective: Obstructive sleep apnea (OSA) is associated with intermittent hypoxia. OSA leads to increased sympathetic activation, oxidative stress, vascular endothelial dysfunction, coagulation disorders and metabolic dysregulation. These disturbances increase the the risk of inflammation and cardiovascular diseases. The purpose of this article is to review the laboratory parameters of OSA patients without any comorbidities. Materials and Methods: This retrospective study of consecutive 675 patients who had polysomnography, was conducted on one hundred and thirty patients who did not have any comorbidities. Laboratory values of patients were evaluated. Patients were grouped according to apnea-hypopnea index (AHI). Group 1 (n= 17) AHI < 5; group 2 (n= 42) AHI= 5-14.9; group 3 (n= 31) AHI= 15-29.9 and group 4 (n= 40) AHI > 30. Results: There were 88 men (67.7%) and 42 women (32.3%) in the study. Mean age, body mass index, Epworth score and AHI were 41.6 +/- 11.3 (16-75), 29.6 +/- 6.3 (17.1-65.7) 9.9 +/- 5.5, 6.2 +/- 11.34, respectively. Serum glucose, cholesterol and triglyceride levels were higher in group 4 (p= 0.03, p= 0.04, p= 0.02, respectively). Uric acid and fibrinogen levels were higher in patients with higher AHI (p= 0.038). Conclusion: Our study indicates that increased blood glucose, uric acid and dyslipidemia are associated with OSA regardless of comorbidities.
dc.identifier.doi10.4274/jtsm.2016.147
dc.identifier.endpage5
dc.identifier.issn2148-1504
dc.identifier.issn2757-850X
dc.identifier.issue1
dc.identifier.startpage1
dc.identifier.urihttps://doi.org/10.4274/jtsm.2016.147
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3916
dc.identifier.volume3
dc.identifier.wosWOS:000407300100002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isotr
dc.publisherGalenos Publ House
dc.relation.ispartofJournal Of Turkish Sleep Medicine-Turk Uyku Tibbi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectObstructive sleep apnea; glucose; uric acid; dyslipidemia; fibrinogen
dc.titleImportance of Labarotory Parameters in Obstructive Sleep Apnea
dc.typeArticle

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