Evaluation of arterial stiffness in patients with generalized anxiety disorder

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dc.contributor.authorYildiz, Sevler
dc.contributor.authorKılıçaslan, Aslı Kazğan
dc.contributor.authorUğur, Kerim
dc.contributor.authorkurt, osman
dc.contributor.authorKILIÇARSLAN, GÜLHAN
dc.date.accessioned2025-10-24T18:03:29Z
dc.date.available2025-10-24T18:03:29Z
dc.date.issued2023
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractPurpose: Generalized anxiety disorder (GAD) is a psychiatric condition where both physical and mental symptoms are observed due to the activation of the sympathetic system. It is known that the disorder affects the cardiovascular system. The present study aimed to analyze arterial stiffness in GAD patients and compare the findings with healthy controls. Materials and Methods: 40 patients diagnosed with GAD and 40 healthy individuals were included in the study. Carotid and femoral artery intima-medial thickness (IMT) and arterial thickness parameters were measured with Doppler ultrasonography. Results: The femoral IMT of the patients was significantly low. Although the carotid IMT was higher in patients when compared to the controls, the difference was not statistically significant. A significant negative correlation was determined between fluoxetine equivalent dose and femoral IMT. There was a correlation between femoral IMT and fluoxetine equivalent dose. Conclusion: Arterial stiffness should be investigated for its potential to indicate cardiovascular risk in GAD. Further comprehensive studies should be conducted to clarify whether atherosclerosis symptoms were associated with the nature of the GAD or prescription medicine.
dc.identifier.doi10.17826/cumj.1219982
dc.identifier.endpage393
dc.identifier.issn2602-3032
dc.identifier.issn2602-3040
dc.identifier.issue2
dc.identifier.startpage385
dc.identifier.trdizinid1197728
dc.identifier.urihttps://doi.org/10.17826/cumj.1219982
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1197728
dc.identifier.urihttps://hdl.handle.net/20.500.12899/2281
dc.identifier.volume48
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofCukurova Medical Journal
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzTR-Dizin_20251023
dc.subjectTıbbi Araştırmalar Deneysel
dc.subjectPatoloji
dc.subjectKlinik Nöroloji
dc.subjectNörolojik Bilimler
dc.subjectKalp ve Kalp Damar Sistemi
dc.subjectPsikoloji
dc.subjectArterial stiffness
dc.subjectcardiovascular risk
dc.subjectgeneralized anxiety disorder
dc.subjectintima–media thickness.
dc.titleEvaluation of arterial stiffness in patients with generalized anxiety disorder
dc.typeArticle

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