Investigation of polycystic liver disease in patients with autosomal dominant polycystic kidney disease using magnetic resonance imaging

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dc.authorid0000-0002-4609-1580en_US
dc.contributor.authorPembegul İrem
dc.contributor.authorUnlu Serkan
dc.contributor.authorIlgar Mehtap
dc.date.accessioned2022-06-07T08:10:45Z
dc.date.available2022-06-07T08:10:45Z
dc.date.issued2022en_US
dc.departmentMTÖ Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractThe most common hereditary kidney illness, disease of autosomal dominant polycystic kidney disease (ADPKD), is associated with numerous cysts that induce kidney size enlargement. The most common extrarenal symptom of ADPKD is liver cysts. A condition in which patients have >20 cysts in the liver is defined as polycystic liver disease (PLD). The goal of this study was to find out how often PLD was in ADPKD patients and whether there was an association between the incidence of PLD and age, sex, and clinical manifestations using magnetic resonance imaging (MRI) results. In this study, the abdominal MRI results of 32 patients with ADPKD who underwent abdominal MRI at Hospital X between January 01, 2020 and September 30, 2021 were retrospectively evaluated by 2 radiologists. Twenty-nine (90.6%) patients had a minimum 1 cyst in the liver, whereas 12 (37.5%) patients had PLD. The women had a greater rate in of PLD than males, and a statistical difference had been observed (p = 0.033). PLD incidence was found to increase with age. The mean ages of patients with and those without PLD were 46.3 and 35.9 years, respectively, and between the foregoing mean age values, a significant difference was detected (p = 0.003). Furthermore, there was no difference between the patients with and those without PLD in terms of the clinical indicators of ADPKD, including total kidney volume and mean rate of glomerular filtration. In conclusion, the incidence of PLD in ADPKD patients was found to be high in our study, and the presence of PLD was not associated with the clinical findings of ADPKD. For this reason, we think that it may be beneficial to perform liver imaging at the time of diagnosis of ADPKD and in their routine follow-up.en_US
dc.identifier.citationIlgar, M., Pembegul, I., & Unlu, S. (2022). Investigation of polycystic liver disease in patients with autosomal dominant polycystic kidney disease using magnetic resonance imaging. Medicine, 11(1), 239-42.en_US
dc.identifier.doi10.5455/medscience.2021.11.378
dc.identifier.endpage242en_US
dc.identifier.issue1en_US
dc.identifier.startpage239en_US
dc.identifier.uri10.5455/medscience.2021.11.378
dc.identifier.urihttps://hdl.handle.net/20.500.12899/1099
dc.identifier.volume11en_US
dc.institutionauthorPembegul, İrem
dc.language.isoenen_US
dc.publisherPembegul, Iremen_US
dc.relation.ispartofMedicine Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMagnetic resonance imaging,en_US
dc.subjectdisease of polycystic kidney,en_US
dc.subjectpolycystic liver diseaseen_US
dc.titleInvestigation of polycystic liver disease in patients with autosomal dominant polycystic kidney disease using magnetic resonance imagingen_US
dc.typeArticleen_US

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