The Clinical Characteristics of Obstructive Sleep Apnea Patients with a Previous Cardiovascular Event

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dc.contributor.authorDuyar, Sezgi Şahin
dc.contributor.authorAksu, Funda
dc.contributor.authorÇİLEKAR, Şule
dc.contributor.authorPazarlı, Ahmet Cemal
dc.contributor.authorSarioglu, Nurhan
dc.contributor.authorDiken, Özlem Erçen
dc.contributor.authorOzturk, Onder
dc.date.accessioned2025-10-24T18:04:00Z
dc.date.available2025-10-24T18:04:00Z
dc.date.issued2022
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractObjective: Obstructive sleep apnea (OSA) and cardiovascular diseases have some common pathophysiologic characteristics and effects on the outcomes of each other. This study is conducted to determine the characteristics of obstructive sleep apnea patients with a history of a cardiovascular event. Materials and Methods: For this multicenter study, the patients with obstructive sleep apnea [apnea-hypopnea index (AHI) >5/hour] who had a history of coronary angioplasty, coronary bypass grafting, or cerebrovascular event after the onset of the symptoms related to OSA were recruited as the study group. The control group included patients without a history of a cardiovascular event. The weight, subjective sleep duration, smoking, and menopausal status, and the presence of comorbidities before and after the cardiovascular event were also questioned during the follow-up visits and by phone calls. This data was compared with the control group. Results: This multicenter study comprised 281 patients (100 study group and 181 control group), 83% of whom had moderate/severe obstructive sleep apnea. Age, family history for cardiovascular event and, Epworth sleepiness scale score were statistically higher in the study group (p<0.001). Polysomnographic data showed that the study group had higher central AHI (p=0.002), non-supine AHI (p=0.017) and lower NREM3% (p=0.001), mean and minimum oxygen saturation (p=0.002). A subgroup analysis proved that polysomnographic data, which had statistically significant differences, can vary according to gender. Conclusion: The results of this study guide for phenotyping obstructive sleep apnea patients with cardiovascular events. It has also been shown that cardiovascular events may have different effects on sleep parameters in women.
dc.identifier.doi10.4274/jtsm.galenos.2021.28199
dc.identifier.endpage146
dc.identifier.issn2148-1504
dc.identifier.issn2148-1504
dc.identifier.issue2
dc.identifier.startpage139
dc.identifier.trdizinid1130267
dc.identifier.urihttps://doi.org/10.4274/jtsm.galenos.2021.28199
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1130267
dc.identifier.urihttps://hdl.handle.net/20.500.12899/2592
dc.identifier.volume9
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTürk Uyku Tıbbı Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzTR-Dizin_20251023
dc.subjectSolunum Sistemi
dc.subjectGenel ve Dahili Tıp
dc.subjectAlerji
dc.subjectSağlık Bilimleri ve Hizmetleri
dc.subjectKalp ve Kalp Damar Sistemi
dc.titleThe Clinical Characteristics of Obstructive Sleep Apnea Patients with a Previous Cardiovascular Event
dc.typeArticle

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