Biomarkers in Hodgkin's Lymphoma
Küçük Resim Yok
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Crc Press-Taylor & Francis Group
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Lymphoma is a type of hematological cancer which occurs in the immune system, and specifically starts in lymphocytes. Lymphoma is basically of two types: Hodgkin's and non-Hodgkin's lymphoma (NHL). This chapter will specifically focus on Hodgkin's lymphoma (HL), whose subtypes are nodular lymphocyte-predominant Hodgkin's lymphoma (NLPHL) and classical Hodgkin's lymphoma (cHL). The characteristic cell types involved in these subtypes are different from each other. Biomarkers are another critical factor in making the correct identification of each subtype. Biomarkers can be categorized into different groups such as origin-related, chromosomal, cytokine, chemokine, and some important pathways-related markers. These biomarkers are not only important to distinguish subtypes but also critical to determine further treatment strategies for disease. Due to the importance of biomarker knowledge, we have reviewed significant HL biomarkers in this chapter.
Açıklama
Anahtar Kelimeler
Hodgkin's lymphoma; biomarker; NLPHL; cHL; pathway; treatment
Kaynak
Cancer Biomarkers: Minimal And Noninvasive Early Diagnosis And Prognosis
WoS Q Değeri
N/A
