Evaluation of lipid levels and LDL-C/HDL-C ratio as possible risk markers of intracerebral hemorrhage
| dc.contributor.author | Adıgüzel, Ahmet | |
| dc.contributor.author | Çıplak, Sibel | |
| dc.contributor.author | Öztürk, Ünal | |
| dc.date.accessioned | 2022-04-25T11:18:37Z | |
| dc.date.available | 2022-04-25T11:18:37Z | |
| dc.date.issued | 2022 | en_US |
| dc.department | MTÖ Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | en_US |
| dc.description.abstract | Purpose: The aim of this study is to analyze the utility of lipid parameters individually and the low-density lipoprotein cholesterol/high-density lipoprotein cholesterol (LDL-C/HDL-C) ratio as a possible risk marker for intracerebral hemorrhages (ICH). Materials and Methods: This was a multicenter, retrospective case-control study that included 226 patients with ICH and 226 controls. Lipid parameters were evaluated after 12 h of fasting in patients whose ICH was confirmed by brain computed tomography, and no underlying vascular, traumatic, or metabolic cause could be found. Results: The mean LDL-C levels and mean total cholesterol (TC) levels did not differ in in the patient and control groups. The mean HDL-C levels in the patient groups were significantly lower whereas triglyceride (TG) levels were significantly higher. In the patient and control groups, LDL-C/HDL-C ratio was 2.65±1.10 and 2.94±1.13 (p=0.006), TG/HDL-C ratio was 3.60±2.72 and 4.47±3.25 (p=0.002), and TC/HDL-C ratio was 4.37±1.49 and 4.83 ± 1.56 (p=0.002), respectively. Conclusion: Increased TG and decreased HDL-C levels were found to be associated with ICHs. However LDL-C/HDL-C, TC/HDL-C, and TG/HDL-C ratios were low in the patient group. Therefore, we can conclude that these lipid ratios give clearer and more significant results in determining the risk of hemorrhage. | en_US |
| dc.identifier.citation | ADIGÜZEL, A., ÇIPLAK, S., & Öztürk, Ü. (2022). Evaluation of lipid levels and LDL-C/HDL-C ratio as possible risk markers of intracerebral hemorrhage. Cukurova Medical Journal, 47(1), 120-127. | en_US |
| dc.identifier.endpage | 127 | en_US |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.startpage | 120 | en_US |
| dc.identifier.uri | https://hdl.handle.net/20.500.12899/1039 | |
| dc.identifier.volume | 47 | en_US |
| dc.institutionauthor | Çıplak, Sibel | |
| dc.language.iso | en | en_US |
| dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | LDL-C/HDL-C ratio | en_US |
| dc.subject | triglyceride/HDL-C ratio | en_US |
| dc.subject | hemorrhagic stroke | en_US |
| dc.subject | cholesterol | en_US |
| dc.subject | cerebrovascular disease | en_US |
| dc.title | Evaluation of lipid levels and LDL-C/HDL-C ratio as possible risk markers of intracerebral hemorrhage | en_US |
| dc.type | Article | en_US |
