Evaluation of Clinical Characteristics and Treatment Approaches of Patients with Infectious Uveitis

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dc.contributor.authorgök, Zarife Ekici
dc.contributor.authorGürbüz, Esra
dc.contributor.authorEkici, Abdurrahman
dc.contributor.authorAYDEMIR, SELAHATTIN
dc.date.accessioned2025-10-24T18:04:18Z
dc.date.available2025-10-24T18:04:18Z
dc.date.issued2025
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractIntroduction: Many bacterial, viral, fungal, and parasitic diseases can cause ocular inflammation with various chorioretinal symptoms. This study evaluated the clinical characteristics of patients with infectious uveitis and the treatment approaches used. Materials and Methods: The study included 156 patients diagnosed with uveitis at the Ophthalmology Clinic of Malatya Turgut Özal University Training and Research Hospital between May 2020 and June 2023. The data of these patients were obtained from the hospital automation system. The diagnosis of infectious uveitis was based on a combination of clinical and laboratory findings. Data on the patients’ laboratory findings and treatment approaches were also examined. Results: Infectious uveitis was detected in 18.5% of the patients. Among these, seven (24.1%) had retinitis due to Toxoplasma gondii, 17 (58.6%) had Herpes simplex, and three (10.3%) had keratouveitis due to Herpes zoster. Bartonella neuroretinitis was observed in one patient. Isolated anterior uveitis was detected in one patient following coronavirus diseases-2019, with no associated systemic disease. A case of serous retinopathy secondary to a choroidal granuloma in a tuberculosis patient was identified but excluded from the study, as the patient was not treated at this clinic. Clindamycin, trimethoprim-sulfamethoxazole, and steroids were administered to patients diagnosed with toxoplasmosis, and antiviral treatment was administered to those diagnosed with uveitis due to Herpes simplex and Herpes zoster. No visual loss was observed in these patients after treatment, except in those who developed corneal scarring. In one patient with full-thickness corneal involvement, uveitis, and cataract, only minimal improvement was observed with treatment, and frequent recurrences were noted during the follow-up period. Conclusion: Early diagnosis, treatment, and close follow-up in infectious uveitis can minimize the adverse prognosis of the disease.
dc.identifier.doi10.5578/flora.2025021297
dc.identifier.endpage200
dc.identifier.issn1300-932X
dc.identifier.issue2
dc.identifier.startpage190
dc.identifier.trdizinid1318143
dc.identifier.urihttps://doi.org/10.5578/flora.2025021297
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1318143
dc.identifier.urihttps://hdl.handle.net/20.500.12899/2784
dc.identifier.volume30
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofFlora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzTR-Dizin_20251023
dc.subjectHerpes zoster
dc.subjectToxoplasmosis
dc.subjectHerpes simplex
dc.subjectInfectious uveitis
dc.titleEvaluation of Clinical Characteristics and Treatment Approaches of Patients with Infectious Uveitis
dc.typeArticle

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